Kirwan Caitriona, O'Keefe Michael
Mater Private Hospital, Dublin, Ireland.
Acta Ophthalmol. 2008 Mar;86(2):215-8. doi: 10.1111/j.1600-0420.2007.01023.x. Epub 2007 Sep 21.
To evaluate and compare corneal hysteresis in patients prior to and following laser in situ keratomileusis (LASIK) and laser-assisted subepithelial keratectomy (LASEK) using the Reichert ocular response analyser (ORA).
Corneal hysteresis was recorded prior to and 3 months after corneal laser refractive surgery for myopia. Preoperative corneal hysteresis was correlated with age and preoperative central corneal thickness (CCT). Postoperative corneal hysteresis was correlated with postoperative CCT in both the LASIK and LASEK treatment groups. The correlations between postoperative change in hysteresis and stromal ablation depth, percentage of tissue ablated, optical zone and patient age were also examined.
A total of 84 eyes of 84 patients were involved in the study. LASIK was performed in 63 eyes and LASEK in 21. Mean preoperative corneal hysteresis of all eyes was 10.8 +/- 1.5 mmHg. Mean age, preoperative CCT, corneal hysteresis and ablation profile were similar in both groups. A statistically significant decrease in hysteresis occurred following LASIK (p < 0.01) and LASEK (p < 0.01) with similar decrements observed in both treatment groups. A moderate correlation was found between postoperative hysteresis and postoperative CCT in LASIK (r = 0.7) and LASEK (r = 0.7) treated eyes. A weak correlation was found between postoperative decrease in hysteresis and the parameters examined.
Corneal hysteresis decreased following LASIK and LASEK. Similar reductions occurred following both procedures, indicating that LASIK involving a thin 120-mum flap did not induce additional biomechanical change. Postoperative reduction in hysteresis did not correlate with the amount or percentage of corneal tissue removed, nor with optical zone or patient age.
使用瑞特眼反应分析仪(ORA)评估和比较准分子原位角膜磨镶术(LASIK)及准分子激光上皮瓣下角膜磨镶术(LASEK)术前和术后患者的角膜滞后。
记录近视患者角膜激光屈光手术术前及术后3个月的角膜滞后情况。术前角膜滞后与年龄及术前中央角膜厚度(CCT)相关。在LASIK和LASEK治疗组中,术后角膜滞后与术后CCT相关。还研究了滞后的术后变化与基质消融深度、消融组织百分比、光学区及患者年龄之间的相关性。
84例患者共84只眼纳入研究。其中63只眼行LASIK,21只眼行LASEK。所有眼术前平均角膜滞后为10.8±1.5 mmHg。两组患者的平均年龄、术前CCT、角膜滞后及消融情况相似。LASIK(p < 0.01)和LASEK(p < 0.01)术后滞后均出现统计学显著下降,且两个治疗组下降幅度相似。在接受LASIK(r = 0.7)和LASEK(r = 0.7)治疗的眼中,术后滞后与术后CCT之间存在中度相关性。术后滞后的下降与所检查参数之间存在弱相关性。
LASIK和LASEK术后角膜滞后均降低。两种手术术后均出现类似程度的降低,表明制作120μm薄瓣的LASIK未引发额外的生物力学改变。术后滞后的降低与切除的角膜组织量或百分比、光学区或患者年龄均无关。