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内脏疼痛性疾病中的中枢敏化

Central sensitisation in visceral pain disorders.

作者信息

Moshiree B, Zhou Q, Price D D, Verne G N

机构信息

Department of Medicine, University of Florida College of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, 1600 SW Archer Rd, HD 602, PO Box 100214, Gainesville, FL 32610-0214, USA.

出版信息

Gut. 2006 Jul;55(7):905-8. doi: 10.1136/gut.2005.078287.

Abstract

The concepts of visceral hyperalgesia and visceral hypersensitivity have been examined in a variety of functional gastrointestinal disorders (FGIDs). Although the pathophysiological mechanisms of pain and hypersensitivity in these disorders are still not well understood, exciting new developments in research have been made in the study of the brain-gut interactions involved in the FGIDs.

摘要

在内脏痛觉过敏和内脏高敏感性的概念已在多种功能性胃肠疾病(FGIDs)中得到研究。尽管这些疾病中疼痛和高敏感性的病理生理机制仍未完全明了,但在FGIDs所涉及的脑-肠相互作用的研究方面已取得了令人振奋的新进展。

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