Keller M B, Lavori P W, Beardslee W R, Wunder J, Ryan N
Brown University, Butler Hospital, Providence, RI 02906.
J Affect Disord. 1991 Mar;21(3):163-71. doi: 10.1016/0165-0327(91)90037-s.
This article reports on the treatment received by 38 adolescents during an episode of major depression which had a median duration of 4 months. The one subject who received any pharmacologic treatment was prescribed an antianxiety agent. Sixteen percent received psychotherapy. These results are consistent with evidence from studies of adults indicating that depression is underrecognized and undertreated. An important caveat is that the small sample size limits the generalizability of these findings. Moreover, which medication should be prescribed when a diagnosis of depression is made is not yet known with certainty, as literature reviews indicate that more controlled trials of psychotherapeutic and psychopharmacologic treatments for adolescents with depression are needed to better understand the efficacy of treating depressed adolescents.
本文报道了38名青少年在一次重度抑郁发作期间接受的治疗情况，该重度抑郁发作的持续时间中位数为4个月。接受任何药物治疗的一名受试者被开了一种抗焦虑药。16%的人接受了心理治疗。这些结果与针对成年人的研究证据一致，表明抑郁症未得到充分认识和治疗。一个重要的告诫是，样本量小限制了这些发现的普遍性。此外，由于文献综述表明，需要更多针对青少年抑郁症的心理治疗和心理药物治疗的对照试验，以更好地了解治疗抑郁青少年的疗效，所以当做出抑郁症诊断时应开哪种药物尚不确定。
