Porwit-Bóbr Z, Radziejowska A, Slowik M
Arch Immunol Ther Exp (Warsz). 1975;23(2):257-61.
The effect of solube antigens from polyoma tumor cells, liver antigens and PHA on lymph node cells from tumor bearers and on normal lymph node cells in CBA mice was studied. The stimulation index was calculated on the basis of incorporation of 14C-leucine in short-term cultures. The stimulation index was lower in lymphocytes derived from tumor bearers than those from normal donors. The blastoid responses to polyoma-associated antigens and PHA were similar, in contrast to liver-associated antigens. It was concluded that stimulation of liver antigens may be connected with different chemical structure, mainly of carbohydrate components.
研究了多瘤肿瘤细胞的可溶性抗原、肝脏抗原和PHA对荷瘤小鼠淋巴结细胞以及CBA小鼠正常淋巴结细胞的影响。基于短期培养中14C-亮氨酸的掺入量计算刺激指数。荷瘤小鼠来源的淋巴细胞的刺激指数低于正常供体来源的淋巴细胞。与肝脏相关抗原相比，对多瘤相关抗原和PHA的母细胞样反应相似。得出的结论是，肝脏抗原的刺激可能与不同的化学结构有关，主要是碳水化合物成分。
