de Castilho Euclides Ayres, Szwarcwald Célia Landmann, de Brito Ana Maria
Secretaria Estadual de Saúde do Rio Grande do Norte, Natal, RN.
Rev Assoc Med Bras (1992). 2006 Mar-Apr;52(2):86-92. doi: 10.1590/s0104-42302006000200017. Epub 2006 Jun 1.
The purpose of this study is to determine factors associated to the interruption of antiretroviral treatment in adults with AIDS in the State of Rio Grande do Norte, Brazil.
This was a population-based study, using data from the State's sources of vital statistics. Interruption was calculated using data on the number of programmed visits to the pharmacies, taking into account the date of the first prescription. It was considered that patients had adhered to the treatment if they came to at least 80% of the programmed visits.
The overall percentage for non interruption of the antiretroviral therapy was 64.1%. No association was found with the following: gender, type of exposure, residence, nor with the type of antiretroviral combination prescribed. After multivariate analysis, significant associations continued to be found between interruption and in-hospital stay, use of drugs, psychiatric treatment, low level of education and age ranging from 25 to 34 years.
These results point towards significant associations between interruption of antiretroviral treatment and the beginning of antiretroviral therapy during the in-hospital stay, the use of legal or illegal drugs, a history of psychiatric treatment, low level of education, and age ranging from 25 to 34 years.
本研究旨在确定巴西北里奥格兰德州成年艾滋病患者抗逆转录病毒治疗中断的相关因素。
这是一项基于人群的研究，使用该州生命统计数据源的数据。根据首次处方日期，利用药房计划就诊次数数据计算中断情况。如果患者至少80%的计划就诊都前来就诊，则认为其坚持了治疗。
抗逆转录病毒治疗未中断的总体百分比为64.1%。未发现与以下因素有关联：性别、暴露类型、居住地以及所开抗逆转录病毒联合用药类型。多变量分析后，仍发现中断与住院、药物使用、精神治疗、低教育水平以及25至34岁年龄之间存在显著关联。
这些结果表明抗逆转录病毒治疗中断与住院期间开始抗逆转录病毒治疗、使用合法或非法药物、有精神治疗史、低教育水平以及25至34岁年龄之间存在显著关联。
