Yokozawa T, Fujitsuka N, Yasui T, Oura H
Department of Applied Biochemistry, Toyama Medical and Pharmaceutical, Japan.
J Pharm Pharmacol. 1991 Apr;43(4):290-1. doi: 10.1111/j.2042-7158.1991.tb06689.x.
In comparison with non-diabetic rats, the tissue ATP content of diabetic rats is lower and the AMP content higher. However, daily intraperitoneal administration of ginsenoside-Rb2 for several days resulted in an increase of tissue ATP content and a decrease of AMP content, characterized by an increase in the adenine nucleotide content, as well as improvement of energy charge. Thus, ginsenoside-Rb2 administration caused a change in the pattern of metabolism, activating the ATP supply system.