Ribera M C, Pascual R, Orozco D, Pérez Barba C, Pedrera V, Gil V
Department of Clinical Medicine, Miguel Hernández University, Campus de San Juan, San Juan, Alicante, 03550, Spain.
Eur J Clin Microbiol Infect Dis. 2006 Jun;25(6):389-93. doi: 10.1007/s10096-006-0148-5.
In order to compare the incidence of symptomatic urinary tract infection (UTI) in diabetic patients with and without asymptomatic bacteriuria (ASB), and to identify other risk factors for these infections, 289 females and 168 males were studied over a 12-month period. Symptomatic UTI occurred in 69.2% of patients with ASB (67.6% female and 76.5% male) versus 9.8% without ASB (14.9% female and 2.6% male). ASB and urinary incontinence were associated with symptomatic UTI in both women and men. Other risk factors included previous antimicrobial treatment and macrovascular complications in women and obesity and prostatic syndrome in men. The presence of ASB was found to be the major risk factor for developing symptomatic urinary tract infection. Further prospective randomized clinical trials of diabetic patients with risk factors for UTI who are receiving or not receiving treatment may be considered.
为比较有无无症状菌尿（ASB）的糖尿病患者发生有症状性尿路感染（UTI）的发生率，并确定这些感染的其他危险因素，在12个月期间对289名女性和168名男性进行了研究。有ASB的患者中69.2%发生了有症状性UTI（女性为67.6%，男性为76.5%），而无ASB的患者中这一比例为9.8%（女性为14.9%，男性为2.6%）。ASB和尿失禁在女性和男性中均与有症状性UTI相关。其他危险因素包括女性既往抗菌治疗和大血管并发症，以及男性肥胖和前列腺综合征。发现ASB的存在是发生有症状性尿路感染的主要危险因素。对于有UTI危险因素且正在接受或未接受治疗的糖尿病患者，可能需要进一步进行前瞻性随机临床试验。
