Wagner Karen Dineen, Martinez Melissa, Joiner Thomas
Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA.
J Child Adolesc Psychopharmacol. 2006 Jun;16(3):298-307. doi: 10.1089/cap.2006.16.298.
This study was designed to prospectively assess youths' and their parents' attitudes and experiences about participation in clinical treatment research.
Pre- and post-questionnaires were administered to 90 youths ages 6-17 years with psychiatric disorders who participated in clinical treatment studies and their parents between August 2000 and March 2004.
The majority of youths (63%) and parents (90%) reported that finding out about the youth's problem and receiving treatment were the main reasons for participation in the clinical treatment studies. Percentage of youths and parents, respectively, who confirmed that informed consent issues were discussed were: Purpose of study (96%, 100%), study procedures (94%, 100%), alternative treatment (62%, 94%), and voluntary participation (89%, 99%). Most youths liked their treatment (98%), believed the study proceeded as expected (67%), were glad to have participated in this study (94%), and would participate in another study (65%). Most parents believed the quality of care was good (90%), the study proceeded as expected (96%), and were glad their child participated (99%).
The majority of youths and parents had a positive view about their experiences of participating in clinical treatment research, independent of whether or not the youth's psychiatric condition improved.
本研究旨在前瞻性评估青少年及其父母对于参与临床治疗研究的态度和经历。
在2000年8月至2004年3月期间，对90名年龄在6至17岁、患有精神疾病且参与临床治疗研究的青少年及其父母进行了前后问卷调查。
大多数青少年（63%）和父母（90%）表示，了解青少年的问题并接受治疗是参与临床治疗研究的主要原因。确认已讨论知情同意问题的青少年和父母的比例分别为：研究目的（96%，100%）、研究程序（94%，100%）、替代治疗（62%，94%）和自愿参与（89%，99%）。大多数青少年喜欢他们的治疗（98%），认为研究按预期进行（67%），很高兴参与了这项研究（94%），并且愿意参与另一项研究（65%）。大多数父母认为护理质量良好（90%），研究按预期进行（96%），并且很高兴他们的孩子参与其中（99%）。
大多数青少年和父母对他们参与临床治疗研究的经历持积极看法，与青少年的精神状况是否改善无关。
