Lim Tao S, Finlayson Andrew, Thorpe James M, Sieunarine Kishore, Mwipatayi Bibombe P, Brady Anne, Abbas Manzoor, Angel Donna
Department of Vascular Surgery, Royal Perth Hospital, Perth, Western Australia, Australia.
ANZ J Surg. 2006 May;76(5):300-5. doi: 10.1111/j.1445-2197.2006.03715.x.
The aim of this study was to determine the outcomes of a contemporary amputation series.
A retrospective audit of 87 cases of major lower limb amputation from January 2000 to December 2002 from the Department of Vascular Surgery, Royal Perth Hospital, was conducted.
The mean age of the study population was 70.1 +/- 14.3 years; the male : female ratio was 3.35:1. Comorbid problems included diabetes (49.4%), smoking (81.6%), hypertension (77.0%), ischaemic heart disease (58.6%), stroke (25.3%), raised creatinine level (34.5%) and chronic airway limitation (25.3%). Preamputation vascular reconstructive procedures were common, 34.5% in a previous admission and 23.0% in the same admission. The main indication was critical limb ischaemia (75.9%) followed by diabetic infection (17.2%). There were 51 below-knee (58.6%), 5 through-knee (5.7%) and 31 above-knee (35.6%.) amputations. The below-knee amputation to above-knee amputation ratio was 1.65:1. The overall wound infection rate was 26.4%; the infection rates for below-knee (29.4%) and above-knee (22.6%) amputation did not differ significantly (P = 0.58). Revision rates were 17.6% for below-knee, 20% for through-knee and none for above-knee amputations. Twenty patients (23.0%) underwent subsequent contralateral amputation. Thirty-nine patients (44.8%) were selected as suitable for a prosthesis by a rehabilitation physician; 31 (79.5%) used the prosthesis both indoors and outdoors and 6 (15.4%) used it indoors only within 3 months. Cumulative mortality at 30 days, 6 months, 12 months and 24 months was 10.1, 28.7, 43.1 and 51.7%, respectively.
This series agrees with the current published work in finding that patients undergoing major lower limb amputation are older, with a high prevalence of comorbid conditions. Successful prosthesis rehabilitation depends on patient selection and a multidisciplinary approach. Despite a low immediate mortality, the overall long-term results of lower limb amputation remain dismal.
本研究旨在确定当代截肢病例系列的结果。
对皇家珀斯医院血管外科2000年1月至2002年12月期间的87例下肢大截肢病例进行回顾性审计。
研究人群的平均年龄为70.1±14.3岁;男女比例为3.35:1。合并症包括糖尿病(49.4%)、吸烟(81.6%)、高血压(77.0%)、缺血性心脏病(58.6%)、中风(25.3%)、肌酐水平升高(34.5%)和慢性气道受限(25.3%)。截肢前血管重建手术很常见,34.5%在之前的入院期间进行,23.0%在同一入院期间进行。主要指征是严重肢体缺血(75.9%),其次是糖尿病感染(17.2%)。有膝下截肢51例(58.6%)、膝部截肢5例(5.7%)和膝上截肢31例(35.6%)。膝下截肢与膝上截肢的比例为1.65:1。总体伤口感染率为26.4%;膝下截肢(29.4%)和膝上截肢(22.6%)的感染率差异无统计学意义(P = 0.58)。膝下截肢的翻修率为17.6%,膝部截肢为20%,膝上截肢无翻修病例。20例患者(23.0%)随后接受了对侧截肢。39例患者(44.8%)被康复医生选为适合安装假肢;31例(79.5%)在3个月内既在室内也在室外使用假肢,6例(15.4%)仅在室内使用假肢。30天、6个月、12个月和24个月时的累积死亡率分别为10.1%、28.7%、43.1%和51.7%。
本系列研究与当前已发表的研究结果一致,即接受下肢大截肢的患者年龄较大,合并症患病率较高。成功的假肢康复取决于患者的选择和多学科方法。尽管近期死亡率较低,但下肢截肢的总体长期结果仍然不佳。