McCurdy Sheryl A, Ross Michael W, Kilonzo Gad Paul, Leshabari M T, Williams Mark L
University of Texas Health Science Center at Houston, School of Public Health, WHO Center for Health Promotion and Prevention Research, Houston, TX 77030, USA.
Drug Alcohol Depend. 2006 Apr;82 Suppl 1:S23-7. doi: 10.1016/s0376-8716(06)80004-9.
This study examines the intersection between needle-sharing practices and HIV recovered from used syringes collected from 73 heroin injection drug users (IDUs) in Dar es Salaam, Tanzania, between October 2003 and January 2004. To extract blood residue, syringes were flushed and 10 microliters of solution mixed with 120 microliters of a latex solution was placed on a Capillus HIV-1/2 slide. Thirty-five (57%) of the useable syringes tested positive for HIV antibodies. Results varied significantly: 90% of syringes tested HIV positive in a mixed-income neighborhood 2 kilometers from the city center: 0% of syringes tested HIV positive in the outlying areas. In addition, semistructured interviews were conducted with 51 IDUs. The interviews were content coded, and codes were collapsed into emergent themes regarding syringe-use practices. Injecting is a recent practice, particularly among heroin users in neighborhoods far from the city center. Sharing syringes has resulted in a high proportion of used syringes containing HIV-positive blood residue. Geographic distance is an indicator of recent adoption of IDU in neighborhoods and correlates strongly with the distribution of syringes containing HIV-positive blood residue.
本研究调查了2003年10月至2004年1月间在坦桑尼亚达累斯萨拉姆从73名海洛因注射吸毒者(IDU)收集的用过的注射器中针头共用行为与HIV检出情况之间的交叉关系。为提取血液残留,将注射器冲洗后,取10微升溶液与120微升乳胶溶液混合,置于Capillus HIV-1/2载玻片上。35支(57%)可用注射器检测出HIV抗体呈阳性。结果差异显著:在距离市中心2公里的一个混合收入社区,90%的注射器检测出HIV呈阳性;在外围地区,0%的注射器检测出HIV呈阳性。此外,还对51名IDU进行了半结构化访谈。对访谈内容进行编码,并将编码归纳为关于注射器使用行为的新出现主题。注射是一种新近出现的行为,尤其是在远离市中心社区的海洛因使用者中。共用注射器导致很大比例的用过的注射器含有HIV阳性血液残留。地理距离是社区近期采用IDU行为的一个指标,并且与含有HIV阳性血液残留的注射器的分布密切相关。