Diaz T, Chu S Y, Weinstein B, Mokotoff E, Jones T S
Centers for Disease Control and Prevention, National Center of HIV, STD, and TB Prevention, Division of HIV/AIDS Prevention, Atlanta, Georgia, USA.
J Acquir Immune Defic Syndr Hum Retrovirol. 1998;18 Suppl 1:S76-81. doi: 10.1097/00042560-199802001-00014.
Because HIV-infected injection drug users (IDUs) can transmit HIV infection, we investigated factors associated with sharing of syringes in the past year among IDUs infected with HIV. We analyzed data from an interview survey of 11,757 persons > or = 18 years of age with HIV or AIDS between June 1990 and August 1995 who were reported to 12 state or city health departments in the United States. Of the 1527 persons who had ever shared syringes and reported injecting in the 5 years before the interview, 786 (51%) had injected in the year before interview, and of these, 391 (50%) had shared during that year. IDUs who were aware of their HIV infection for >1 year were less likely to share (43%) than those who were aware of their infection for 1 year or less (65%, adjusted odds ratio=2.15, 95% confidence interval, 1.52-3.03). The only statistically significant time trend was that the proportion of IDUs from Connecticut who shared decreased from 71% in 1992 to 29% in 1995. This trend appears to be related to the 1992 changes in Connecticut laws that allowed purchase and possession of syringes without a prescription. Because many HIV-infected IDUs continue to inject and share, prevention efforts should be aimed at HIV-infected IDUs to prevent transmission of HIV. Early HIV diagnosis and access to sterile syringes may be important methods for reducing syringe sharing by HIV-infected IDUs.
由于感染艾滋病毒的注射吸毒者能够传播艾滋病毒感染,我们调查了过去一年中感染艾滋病毒的注射吸毒者共用注射器的相关因素。我们分析了1990年6月至1995年8月期间向美国12个州或城市卫生部门报告的11757名年龄在18岁及以上的艾滋病毒或艾滋病感染者的访谈调查数据。在1527名曾经共用注射器且在访谈前5年内报告有注射行为的人中,786人(51%)在访谈前一年有注射行为,其中391人(50%)在那一年共用过注射器。知晓自己感染艾滋病毒超过1年的注射吸毒者共用注射器的可能性(43%)低于知晓感染1年或更短时间的注射吸毒者(65%,调整后的优势比=2.15,95%置信区间为1.52 - 3.03)。唯一具有统计学显著意义的时间趋势是,来自康涅狄格州的注射吸毒者共用注射器的比例从1992年的71%降至1995年的29%。这一趋势似乎与1992年康涅狄格州法律的变化有关,该法律允许无需处方购买和持有注射器。由于许多感染艾滋病毒的注射吸毒者仍继续注射和共用注射器,预防工作应针对感染艾滋病毒的注射吸毒者以防止艾滋病毒传播。早期艾滋病毒诊断和获取无菌注射器可能是减少感染艾滋病毒的注射吸毒者共用注射器的重要方法。