Murgu Septimiu D, Colt Henri G
Pulmonary and Critical Care Medicine, Department of Medicine, University of California School of Medicine, Irvine, CA, USA.
Respirology. 2006 Jul;11(4):388-406. doi: 10.1111/j.1440-1843.2006.00862.x.
Tracheobronchomalacia and excessive dynamic airway collapse are two separate forms of dynamic central airway obstruction that may or may not coexist. These entities are increasingly recognized as asthma and COPD imitators. The understanding of these disease processes, however, has been compromised over the years because of uncertainties regarding their definitions, pathogenesis and aetiology. To date, there is no standardized classification, diagnosis or management algorithm. In this article we comprehensively review the aetiology, morphopathology, physiology, diagnosis and treatment of these entities.
气管支气管软化和过度动态气道塌陷是动态中央气道阻塞的两种不同形式,它们可能共存,也可能不共存。这些病症越来越被认为是哮喘和慢性阻塞性肺疾病的模仿者。然而,由于多年来在其定义、发病机制和病因方面存在不确定性,对这些疾病过程的理解受到了影响。迄今为止,尚无标准化的分类、诊断或管理算法。在本文中,我们全面回顾了这些病症的病因、形态病理学、生理学、诊断和治疗。