Poulsen P H, Thomsen P D, Olsen J
Division of Animal Genetics, Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
Cytogenet Cell Genet. 1991;57(1):44-6. doi: 10.1159/000133112.
The porcine aminopeptidase N (PEPN) gene was shown to be syntenic with the porcine major histocompatibility complex (SLA) using Southern blot analysis of a pig x mouse hybrid cell panel. Regional localization of the PEPN gene to 7cen----q21 was performed by in situ hybridization. The results suggest that synteny of the genes for mannose phosphate isomerase and PEPN is conserved in pig and man.
利用猪与小鼠杂交细胞系的Southern印迹分析表明,猪氨肽酶N(PEPN)基因与猪主要组织相容性复合体(SLA)同线。通过原位杂交将PEPN基因定位到7cen----q21区域。结果表明,猪和人中磷酸甘露糖异构酶和PEPN基因的同线性是保守的。