McManus I C, Stubbings G F, Martin N
University College London, UK.
J Health Psychol. 2006 May;11(3):467-82. doi: 10.1177/1359105306063320.
Primary ciliary dyskinesia (PCD) causes chronic cough, sinusitis and bronchiectasis, and half of patients also show situs inversus. The genetic basis and visible and concealed chronic symptoms provide potential for stigmatization. We describe a structural equation model linking a questionnaire measure of stigmatization to sex, age, personality (Big Five), symptoms (St George's Respiratory Questionnaire), health status (SF-36) and stress (GHQ-12). Stigma did not relate to physical symptoms or health, or to situs, but correlated with mental health and the social impact of symptoms. Neuroticism, extroversion, openness to experience, age, age at diagnosis and being female indirectly affected stigmatization via mental health.
原发性纤毛运动障碍（PCD）会导致慢性咳嗽、鼻窦炎和支气管扩张，半数患者还会出现脏器反位。其遗传基础以及明显和隐匿的慢性症状都可能导致污名化。我们描述了一个结构方程模型，该模型将污名化的问卷调查指标与性别、年龄、人格（大五人格）、症状（圣乔治呼吸问卷）、健康状况（SF-36）和压力（一般健康问卷-12）联系起来。污名化与身体症状、健康状况或脏器反位无关，但与心理健康以及症状的社会影响相关。神经质、外向性、开放性、年龄、诊断年龄以及女性身份会通过心理健康间接影响污名化。
