Takeda Takayuki, Nishimura Yoshihiro, Satouchi Miyako, Kamiryo Hiroshi, Takenaka Kaori, Kasai Daisuke, Urata Yoshiko, Kobayashi Kazuyuki, Shimada Temiko, Yoshimura Sho, Nishiuma Teruaki, Yokoyama Mitsuhiro
Division of Cardiovascular and Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Am J Med Sci. 2006 Jun;331(6):304-8. doi: 10.1097/00000441-200606000-00002.
We evaluated the usefulness of oximetry tests that are frequently used as screening tools for sleep apnea syndrome (SAS) by determining the level of agreement between oximetry test results and polysomnography test (PSG) results. We retrospectively examined 135 patients suspected of having SAS. Although the oximetry desaturation index (DSI) seemed better than the oximetry apnea index in the agreement with the polysomnography respiratory disturbance index (RDI), the criteria of DSI greater than or equal to 15 was not sensitive enough to screen for moderate SAS (PSG-RDI >or= 20). Multivariate analyses revealing that body mass index (BMI) as well as DSI correlated well with PSG-RDI, we established a new criterion by adding the BMI score (DSI >or= 15 or BMI >or= 25), which remarkably improved the sensitivity. This criterion may be useful not only in clinical practice but also in medical checkups for asymptomatic patients, and also suggests that obese patients with sleep disturbance should undergo PSGs, irrespective of the DSI score.
我们通过确定血氧饱和度测试结果与多导睡眠图测试（PSG）结果之间的一致性水平，评估了经常用作睡眠呼吸暂停综合征（SAS）筛查工具的血氧饱和度测试的实用性。我们回顾性研究了135例疑似患有SAS的患者。尽管在与多导睡眠图呼吸紊乱指数（RDI）的一致性方面，血氧饱和度下降指数（DSI）似乎比血氧饱和度呼吸暂停指数更好，但DSI大于或等于15的标准对于筛查中度SAS（PSG-RDI≥20）不够敏感。多变量分析显示体重指数（BMI）以及DSI与PSG-RDI相关性良好，我们通过添加BMI评分（DSI≥15或BMI≥25）建立了一个新的标准，这显著提高了敏感性。该标准不仅在临床实践中有用，而且在无症状患者的体检中也有用，还表明有睡眠障碍的肥胖患者无论DSI评分如何都应接受PSG检查。
