Heliomare, Postbus 78, 1940 AB Beverwijk, the Netherlands.
Stroke. 2012 Sep;43(9):2491-3. doi: 10.1161/STROKEAHA.112.665414. Epub 2012 Jul 19.
Sleep apnea syndrome (SAS) is a common sleep disorder in stroke patients and is associated with decreased recovery and increased risk of recurrent stroke and mortality. The standard diagnostic test for SAS is poly(somno)graphy, but this is often not feasible in stroke rehabilitation settings. This study investigated the diagnostic value of nocturnal oximetry for screening SAS in stroke rehabilitation.
Fifty-six stroke patients underwent nocturnal polygraphy and oximetry. Sensitivity, specificity, and positive and negative predictive values for the oxygen desaturation index were calculated. Patient and sleep characteristics were used to develop a predictive model of apnea-hypopnea index.
Forty-six percent of the stroke patients had SAS. The majority of SAS patients was male, older, and had a higher body mass index than patients without SAS. Sensitivity, specificity, and positive and negative predictive values for the oxygen desaturation index ≥15 were, respectively, 77%, 100%, 100%, and 83%. Oxygen desaturation index predicted 87% of the variance in the apnea-hypopnea index. Patient characteristics did not add significantly to the prediction model.
Nocturnal oximetry is an accurate diagnostic screening instrument for the detection of SAS in stroke patients.
睡眠呼吸暂停综合征（SAS）是中风患者中常见的睡眠障碍，与康复效果下降以及中风复发和死亡风险增加有关。SAS 的标准诊断测试是多导睡眠图，但在中风康复环境中，这通常不可行。本研究探讨了夜间血氧仪筛查中风康复患者 SAS 的诊断价值。
56 名中风患者接受了夜间多导睡眠图和血氧仪检查。计算了氧减指数的敏感性、特异性、阳性预测值和阴性预测值。利用患者和睡眠特征建立了呼吸暂停低通气指数的预测模型。
46%的中风患者患有 SAS。与无 SAS 的患者相比，SAS 患者中大多数为男性、年龄较大、体重指数较高。氧减指数≥15 的敏感性、特异性、阳性预测值和阴性预测值分别为 77%、100%、100%和 83%。氧减指数预测了呼吸暂停低通气指数的 87%的方差。患者特征并未显著增加预测模型的预测能力。
夜间血氧仪是检测中风患者 SAS 的一种准确的诊断筛查工具。
