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DNA polymorphisms in the epsilon- and gamma-globin gene regions in Asian macaques.

作者信息

Shimizu K, Takenaka O

机构信息

Department of Morphology, Institute for Developmental Research, Aichi Prefectural Colony, Japan.

出版信息

Biochem Genet. 1991 Apr;29(3-4):189-202. doi: 10.1007/BF02401812.

DOI:10.1007/BF02401812
PMID:1677561
Abstract

DNA polymorphisms in the epsilon- and gamma-globin gene regions in nine Asian macaques (Macaca fuscata, M. mulatta, M. nemestrina, M. cyclopis, M. fascicularis, M. arctoides, M. radiata, M. maura, and M. assamensis) were examined using several different restriction endonucleases and the human epsilon and gamma IVS2 probes. M. fuscata and M. mulatta had highly polymorphic sites (BglII and HincII, respectively) in the epsilon-globin gene region. The BamHI site in the gamma-globin gene region was highly polymorphic in M. mulatta, while the BglII and HindIII sites in the gamma-globin gene region were highly polymorphic in M. fuscata and M. mulatta. The presence of the gamma-globin gene triplication was frequently observed in M. fuscata. The gain or loss of an additional BglII site between two gamma-globin genes in Asian macaques seems to be very meaningful for discussing genetic relationships among them.

摘要

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本文引用的文献

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