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红毛猩猩胎儿血红蛋白的Vγ链

The V gamma chain of fetal hemoglobin of the orangutan.

作者信息

Schroeder W A, Shelton J R, Shelton J B, Huisman T H

出版信息

Biochem Genet. 1978 Dec;16(11-12):1203-5. doi: 10.1007/BF00484540.

Abstract

Previous studies suggested that orangutans have nonallelic structural genes for their gamma chains, because either a threonyl or an alanyl residue may occupy position 135. Further investigation has now detected that position 75 may have either an isoleucyl or a valyl residue. From available evidence, the isoleucyl and threonyl residues are in one chain an the valyl and alanyl in the other. Orangutans appear to be homozygous for the two types of nonallelic genes.

摘要

先前的研究表明,红毛猩猩的γ链具有非等位结构基因,因为在第135位可能是苏氨酰残基或丙氨酰残基。现在进一步的研究发现,第75位可能是异亮氨酰残基或缬氨酰残基。从现有证据来看,一条链上是异亮氨酰和苏氨酰残基,另一条链上是缬氨酰和丙氨酰残基。红毛猩猩似乎对于这两种非等位基因是纯合的。

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