Hoppe Hanno, Nutting Charles W, Smouse H Robert, Vesely Thomas M, Pohl Christoph, Bettmann Michael A, Kaufman John A
Dotter Interventional Institute, Oregon Health Science University, Portland 97239-3098, USA.
J Vasc Interv Radiol. 2006 Jun;17(6):1017-23. doi: 10.1097/01.rvi.90000223689.49091.76.
To evaluate the safety and effectiveness of retrieval of the Günther Tulip inferior vena cava (IVC) filter.
This was a nonrandomized, single-armed, multicenter prospective investigation. Patients at temporary high risk for pulmonary embolism (PE) or deep vein thrombosis (DVT) who did not require a permanent filter were eligible. Forty-one patients received 42 Günther Tulip filters: 22 men and 19 women with a mean age of 47.7 years. Indications for filter placement included prophylaxis, PE, and DVT. Three months after filter retrieval, contrast agent-enhanced computed tomography of the abdomen, jugular vein ultrasonography, and clinical follow-up were performed.
The filter retrieval rate was 57% (23 of 41). Günther Tulip filters were removed at a mean of 11.1 days (range, 2-14 d). The technical and clinical success rates for filter retrieval were both 100%. One placement complication and two protocol deviations occurred. These patients were excluded in terms of retrieval-related outcomes. One case of PE occurred with a filter in place, and one filter migrated to the heart. There were no acute complications caused by filter retrieval. At 3-month follow-up, there was no recurrent PE, DVT, jugular vein occlusion, or IVC stenosis or occlusion.
In this multicenter study, retrieval of the Günther Tulip filter was safe and without recurrent thromboembolic events or evidence of IVC or jugular vein damage at 3-month follow-up.
评估取出Günther Tulip下腔静脉（IVC）滤器的安全性和有效性。
这是一项非随机、单臂、多中心前瞻性研究。符合条件的患者为有肺栓塞（PE）或深静脉血栓形成（DVT）短期高风险且不需要永久性滤器的患者。41例患者植入了42枚Günther Tulip滤器：男性22例，女性19例，平均年龄47.7岁。植入滤器的指征包括预防、PE和DVT。滤器取出3个月后，进行腹部对比剂增强计算机断层扫描、颈静脉超声检查和临床随访。
滤器取出率为57%（41例中的23例）。Günther Tulip滤器平均在11.1天（范围2 - 14天）取出。滤器取出的技术成功率和临床成功率均为100%。发生了1例植入并发症和2例方案偏离。这些患者在与取出相关的结果方面被排除。1例患者在滤器在位时发生PE，1枚滤器迁移至心脏。滤器取出未引起急性并发症。在3个月随访时，无复发性PE、DVT、颈静脉闭塞或IVC狭窄或闭塞。
在这项多中心研究中，Günther Tulip滤器取出是安全的，在3个月随访时无复发性血栓栓塞事件，也无IVC或颈静脉损伤的证据。
