Baldree L A, Gaber L W, McKay C P
Department of Pediatrics, LeBonheur Children's Medical Center, University of Tennessee, Memphis.
Pediatr Nephrol. 1991 May;5(3):296-9. doi: 10.1007/BF00867482.
We report a case of pauci-immune, necrotizing and crescentic glomerulonephritis in a 10-year-old child initially thought to have Henoch-Schönlein purpura. The diagnosis of a Wegener's granulomatosis-microscopic polyarteritis disorder was made on the basis of clinical presentation and a positive anti-neutrophil cytoplasmic autoantibody (ANCA). This case illustrates the usefulness of the ANCA in the diagnosis and management of childhood vasculitides.
我们报告了一例10岁儿童的寡免疫性、坏死性和新月体性肾小球肾炎,该患儿最初被认为患有过敏性紫癜。根据临床表现和抗中性粒细胞胞浆自身抗体(ANCA)阳性,诊断为韦格纳肉芽肿-显微镜下多动脉炎疾病。该病例说明了ANCA在儿童血管炎诊断和管理中的作用。