Henke L, Cleef S, Zakrzewska M, Henke J
Institut f. Blutgruppenforschung, Düsseldorf, Germany.
EXS. 1991;58:144-53. doi: 10.1007/978-3-0348-7312-3_11.
We report on the population genetic data (frequencies of restriction fragments, heterozygosity rates, and mutation rates) obtained by analysis of approximately 1100 Hinfl-digested DNAs from West Germans. Probe G3 detects a common 1.7 kb DNA fragment showing a population frequency of about 13%. All the other fragments detected with probes MS1, MS31, MS43, G3 and YNH24 show frequencies of less than 8%. These data suggest that single locus DNA probes can provide valuable information for parentage evaluation and individualization.
我们报告了通过分析约1100份来自西德人的经Hinfl酶切的DNA所获得的群体遗传数据(限制性片段频率、杂合率和突变率)。探针G3检测到一个常见的1.7 kb DNA片段,其群体频率约为13%。用探针MS1、MS31、MS43、G3和YNH24检测到的所有其他片段的频率均低于8%。这些数据表明,单基因座DNA探针可为亲子鉴定和个体识别提供有价值的信息。