Boone John M, Lindfors Karen K
University of California, Davis, Radiology Research, UC Davis Medical Center, Sacramento, CA 95817, USA.
Future Oncol. 2006 Jun;2(3):351-6. doi: 10.2217/14796694.2.3.351.
Although screening mammography has been shown to be effective in reducing breast cancer mortality, a new technique called breast computed tomography (CT) is being studied in the hope that breast cancer can be detected even earlier. A prototype unit has been designed, fabricated and tested at the University of California, Davis, USA, and is currently being used in a Phase II clinical trial to study the feasibility of breast CT for breast cancer detection and diagnosis. A total of 46 volunteers and patients have been imaged, and the breast CT images show impressive anatomical detail of the breast that is not appreciated in mammography. The radiation dose levels needed to produce excellent image quality are equal to two-view mammography. Further study of breast CT is needed to better understand its potential role in breast cancer screening and diagnosis.
尽管筛查性乳腺钼靶已被证明在降低乳腺癌死亡率方面有效,但一种名为乳腺计算机断层扫描(CT)的新技术正在研究中,希望能更早地检测出乳腺癌。美国加利福尼亚大学戴维斯分校设计、制造并测试了一台原型设备,目前该设备正在进行II期临床试验,以研究乳腺CT用于乳腺癌检测和诊断的可行性。共有46名志愿者和患者接受了成像,乳腺CT图像显示出乳腺令人印象深刻的解剖细节,这在乳腺钼靶检查中是看不到的。产生优异图像质量所需的辐射剂量水平与双视角乳腺钼靶检查相当。需要对乳腺CT进行进一步研究,以更好地了解其在乳腺癌筛查和诊断中的潜在作用。