Chang C H, Sibala J L, Fritz S L, Dwyer S J, Templeton A W, Lin F, Jewell W R
Cancer. 1980 Aug 15;46(4 Suppl):939-46. doi: 10.1002/1097-0142(19800815)46:4+<939::aid-cncr2820461315>3.0.co;2-l.
From October 1, 1976 through July 31, 1979, at the University of Kansas Medical Center, CT/M examinations were performed on 1625 patients. Seventy-eight cancers were histologically diagnosed. A CT/M study using our contrast medium enhancement technique yields both static anatomical changes and dynamic measurements of abnormal iodide concentrations in the breast cancers. This unique ability of CT/M provides many advantages as compared with conventional mammography in the diagnosis of breast cancer. The detection rate in 78 cancers by CT/M was 94% and 77% for the mammography. The CT/M appears to be specially superior to the mammography for detecting cancers in dense, premenopausal dysplastic breasts. The CT/M can detect totally unsuspected very small breast cancers that were unable to be identified by conventional mammography or physical examinations. The CT/M scan also seems to be a better test for recognizing precancerous high risk lesions. CT/M evaluation affords definitive diagnostic help in instances where the mammographic and/or physical examinations are inconclusive. Although CT/M will not replace conventional mammography in routine breast examinations, it overcomes the limitation of mammography.
1976年10月1日至1979年7月31日期间，堪萨斯大学医学中心对1625名患者进行了CT/M检查。经组织学诊断出78例癌症。使用我们的造影剂增强技术进行的CT/M研究可产生静态解剖学变化以及乳腺癌中异常碘浓度的动态测量结果。与传统乳腺摄影相比，CT/M的这种独特能力在乳腺癌诊断中具有许多优势。CT/M对78例癌症的检出率为94%，乳腺摄影的检出率为77%。对于检测致密的绝经前发育异常乳房中的癌症，CT/M似乎特别优于乳腺摄影。CT/M能够检测出传统乳腺摄影或体格检查无法识别的完全未被怀疑的非常小的乳腺癌。CT/M扫描在识别癌前高危病变方面似乎也是一种更好的检查方法。在乳腺摄影和/或体格检查结果不明确的情况下，CT/M评估能提供明确的诊断帮助。虽然CT/M不会在常规乳腺检查中取代传统乳腺摄影，但它克服了乳腺摄影的局限性。
