Tilley Steven, Sisniega Alejandro, Siewerdsen Jeffrey H, Webster Stayman J
Department of Biomedical Engineering, Johns Hopkins University.
Conf Proc Int Conf Image Form Xray Comput Tomogr. 2018 May;2018:318-322.
Detector lag and gantry motion during x-ray exposure and integration both result in azimuthal blurring in CT reconstructions. These effects can degrade image quality both for high-resolution features as well as low-contrast details. In this work we consider a forward model for model-based iterative reconstruction (MBIR) that is sufficiently general to accommodate both of these physical effects. We integrate this forward model in a penalized, weighted, nonlinear least-square style objective function for joint reconstruction and correction of these blur effects. We show that modeling detector lag can reduce/remove the characteristic lag artifacts in head imaging in both a simulation study and physical experiments. Similarly, we show that azimuthal blur ordinarily introduced by gantry motion can be mitigated with proper reconstruction models. In particular, we find the largest image quality improvement at the periphery of the field-of-view where gantry motion artifacts are most pronounced. These experiments illustrate the generality of the underlying forward model, suggesting the potential application in modeling a number of physical effects that are traditionally ignored or mitigated through pre-corrections to measurement data.
在X射线曝光和积分过程中,探测器滞后和机架运动会导致CT重建中的方位模糊。这些效应会降低高分辨率特征以及低对比度细节的图像质量。在这项工作中,我们考虑了一种基于模型的迭代重建(MBIR)的前向模型,该模型具有足够的通用性,能够兼顾这两种物理效应。我们将此前向模型集成到一个惩罚加权非线性最小二乘风格的目标函数中,用于联合重建和校正这些模糊效应。我们表明,在模拟研究和物理实验中,对探测器滞后进行建模都可以减少/消除头部成像中的特征性滞后伪影。同样,我们表明,通过适当的重建模型可以减轻通常由机架运动引入的方位模糊。特别是,我们发现在视野边缘处图像质量改善最大,因为那里的机架运动伪影最为明显。这些实验说明了基础前向模型的通用性,表明其在对许多传统上被忽略或通过对测量数据进行预校正来减轻的物理效应进行建模方面具有潜在应用。