Chang C H, Nesbit D E, Fisher D R, Fritz S L, Dwyer S J, Templeton A W, Lin F, Jewell W R
AJR Am J Roentgenol. 1982 Mar;138(3):553-8. doi: 10.2214/ajr.138.3.553.
The technique for computed tomographic (CT) examination of the breasts using a conventional body scanner is described, and experience with 67 patients is reported. In the diagnosis of both malignant and benign breast lesions, the results with a body scanner were equal to those of a dedicated CT/M mammographic unit. Although the CT study of the breast cannot replace conventional mammography in screening or in routine diagnostic workup, the unique capability of demonstrating both anatomic changes and increased iodide concentration in a cancer provides many advantages over conventional mammography. CT mammography appears to have the capability to detect breast cancers that are occult to other methods. Indications for a CT study of the breasts are: (1) clinically suspected breast cancer, especially with a mammographically occult lesion; (2) questionable mammographic findings, including microcalcifications, tumor shape, architectural distortion, and uncertain lesion location; and (3) evaluation of postbiopsy or postlumpectomy breast cancers when a primary irradiation therapy is contemplated. Breast CT also appears to be a valuable diagnostic tool in searching for a second primary breast cancer, follow-up study of postirradiation of breast cancer, followup study for postmastectomy patients, and screening procedure for genetically high-risk patients, especially those with dense breasts.
本文描述了使用传统全身扫描仪进行乳房计算机断层扫描（CT）检查的技术，并报告了67例患者的经验。在诊断乳腺良恶性病变方面，全身扫描仪的结果与专用CT/M乳腺摄影设备的结果相当。虽然乳腺CT研究不能替代传统乳腺摄影进行筛查或常规诊断检查，但它独特的能够显示解剖结构变化和癌症中碘浓度增加的能力，相比传统乳腺摄影具有许多优势。CT乳腺摄影似乎有能力检测出其他方法难以发现的乳腺癌。乳腺CT研究的适应证包括：（1）临床怀疑乳腺癌，尤其是乳腺摄影隐匿性病变；（2）乳腺摄影结果可疑，包括微钙化、肿瘤形态、结构扭曲和病变位置不确定；（3）考虑进行原发性放射治疗时，对活检后或乳房肿块切除术后的乳腺癌进行评估。乳腺CT在寻找第二原发性乳腺癌、乳腺癌放疗后随访研究、乳房切除术后患者随访研究以及对遗传高危患者（尤其是乳腺致密者）进行筛查程序方面，似乎也是一种有价值的诊断工具。
