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台湾地区2型糖尿病确诊发病率上升:一项全国队列数据分析

Increasing incidence of diagnosed type 2 diabetes in Taiwan: analysis of data from a national cohort.

作者信息

Tseng C-H, Tseng C-P, Chong C-K, Huang T-P, Song Y-M, Chou C-W, Lai S-M, Tai T-Y, Cheng J-C

机构信息

Department of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, Taiwan, Republic of China.

出版信息

Diabetologia. 2006 Aug;49(8):1755-60. doi: 10.1007/s00125-006-0314-4. Epub 2006 Jun 21.

Abstract

AIMS/HYPOTHESIS: Epidemiological evidence shows an increasing prevalence of type 2 diabetes in Taiwan. The aim of this study was to assess the yearly incidence for this country during 1992-1996.

SUBJECTS AND METHODS

Data obtained by telephone interviews of 93,484 diagnosed diabetic patients enrolled in Taiwan's National Health Insurance programme formed the basis of this study. A total of 36,153 incident cases of type 2 diabetes (17,097 men and 19,056 women) were identified and incidence rates calculated. The trends of obesity and parental diabetes were also evaluated.

RESULTS

The overall 5-year incidences for men and women were 187.1 and 218.4 per 100,000 population, respectively. The trends from 1992-1996 were increased for all age groups in men and for most age groups in women. A 2.8-fold increase in incidence was observed for the youngest age group (<35 years), in which the increase in incidence was higher than in the older age groups. Men showed a higher fold increase in incidence than did women (3.5 vs 2.1). Obesity at interview increased from 39.2% in 1992 to 47.6% in 1996 (p<0.001) and was significant for all ages. Parental diabetes showed no yearly change when all patients were analysed together, but there was a trend towards a decrease in the youngest age group (<35 years) and a trend towards an increase in the oldest age groups (>/=55 years).

CONCLUSIONS/INTERPRETATION: An increasing incidence of diagnosed type 2 diabetes was observed for each sex in most age groups in Taiwan, but was most marked in the youngest age group. A parallel increase in obesity was observed with the increasing incidence of diabetes.

摘要

目的/假设:流行病学证据表明,台湾2型糖尿病的患病率呈上升趋势。本研究的目的是评估该国1992 - 1996年期间的年发病率。

对象与方法

通过电话访谈台湾国民健康保险计划登记的93484例确诊糖尿病患者获得的数据构成了本研究的基础。共识别出36153例2型糖尿病新发病例(男性17097例,女性19056例),并计算发病率。还评估了肥胖和父母患糖尿病的趋势。

结果

男性和女性的总体5年发病率分别为每10万人187.1例和218.4例。1992 - 1996年期间,男性所有年龄组以及女性大多数年龄组的发病率呈上升趋势。最年轻年龄组(<35岁)的发病率增加了2.8倍,该年龄组发病率的增幅高于老年组。男性发病率的增幅高于女性(3.5倍对2.1倍)。访谈时的肥胖率从1992年的39.2%上升至1996年的47.6%(p<0.001),且在所有年龄段均有显著变化。当对所有患者进行综合分析时,父母患糖尿病情况没有逐年变化,但最年轻年龄组(<35岁)有下降趋势,而最年长年龄组(≥55岁)有上升趋势。

结论/解读:在台湾,大多数年龄组的男女确诊2型糖尿病发病率均呈上升趋势,但在最年轻年龄组最为明显。随着糖尿病发病率的上升,肥胖率也相应增加。

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