Hogstrom Kenneth R, Almond Peter R
Department of Physics and Astronomy, Louisiana State University, Baton Rouge, LA 70803-4001, USA.
Phys Med Biol. 2006 Jul 7;51(13):R455-89. doi: 10.1088/0031-9155/51/13/R25. Epub 2006 Jun 20.
For over 50 years, electron beams have been an important modality for providing an accurate dose of radiation to superficial cancers and disease and for limiting the dose to underlying normal tissues and structures. This review looks at many of the important contributions of physics and dosimetry to the development and utilization of electron beam therapy, including electron treatment machines, dose specification and calibration, dose measurement, electron transport calculations, treatment and treatment-planning tools, and clinical utilization, including special procedures. Also, future changes in the practice of electron therapy resulting from challenges to its utilization and from potential future technology are discussed.
五十多年来,电子束一直是一种重要的治疗手段,可用于为浅表癌症和疾病提供精确的辐射剂量,并限制对深层正常组织和结构的剂量。本综述探讨了物理和剂量学对电子束治疗的发展和应用所做出的许多重要贡献,包括电子治疗机、剂量规范与校准、剂量测量、电子传输计算、治疗和治疗计划工具以及临床应用(包括特殊程序)。此外,还讨论了电子治疗实践中因应用挑战和未来潜在技术而可能发生的变化。