Sjöström David, Bjelkengren Ulf, Ottosson Wiviann, Behrens Claus F
Department of Oncology (R), Division of Radiophysics (51AA), Copenhagen University Hospital, Herlev, Denmark.
Acta Oncol. 2009;48(2):192-200. doi: 10.1080/02841860802258794.
The flexibility in radiotherapy can be improved if a patient can be moved between any one of the department's medical linear accelerators without the need to change anything in the patient's treatment plan. For this to be possible, the dosimetric characteristics of the various accelerators must be the same, or nearly the same i.e. the accelerators must be beam-matched. During a period of nine months, eight Varian iX accelerators with 6 and 15 MV photon beams and 6-18 MeV electron beams (only four of the eight) were installed at our clinic. All accelerators fulfilled the vendor-defined "fine beam-match" criteria, and a more extensive set of measurements was carried out during commissioning. The measured absorbed dose data for each accelerator were compared with the first accelerator, chosen as reference, and the TPS calculations. Two of the eight accelerators showed a larger discrepancy for the 15 MV beam not revealed by the vendor-defined acceptance criteria, whereas the other six accelerators were satisfactorily matched. The beam-matching acceptance criteria defined by the vendor are not strict enough to guarantee optimal beam-match. Deviations related to dose calculations and to beam-matched accelerators may add up. The safest and most practical way to ensure that all accelerators are within clinical acceptable accuracy is to include TPS calculations in the evaluation. Further, comparisons between measurements and calculations should be done in absolute dose terms.
如果患者能够在科室的任何一台医用直线加速器之间移动,而无需改变患者的治疗计划,那么放射治疗的灵活性就能得到提高。要实现这一点,各种加速器的剂量学特征必须相同,或几乎相同,即加速器必须进行射束匹配。在九个月的时间里,我们诊所安装了八台Varian iX加速器,它们具有6和15 MV光子束以及6 - 18 MeV电子束(八台中的四台)。所有加速器均符合供应商定义的“精细射束匹配”标准,并在调试期间进行了更广泛的测量。将每台加速器的测量吸收剂量数据与选为参考的第一台加速器以及治疗计划系统(TPS)的计算结果进行比较。八台加速器中有两台在15 MV射束方面显示出供应商定义的验收标准未揭示的较大差异,而其他六台加速器的匹配情况令人满意。供应商定义的射束匹配验收标准不够严格,无法保证最佳射束匹配。与剂量计算和射束匹配加速器相关的偏差可能会累积。确保所有加速器在临床可接受精度范围内的最安全、最实用的方法是在评估中纳入TPS计算。此外,测量和计算之间的比较应以绝对剂量的形式进行。