Kahler Christopher W, Strong David R
Center for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island 02912, USA.
Alcohol Clin Exp Res. 2006 Jul;30(7):1165-75. doi: 10.1111/j.1530-0277.2006.00140.x.
Questions persist about the diagnoses of alcohol abuse and alcohol dependence as defined by Diagnostic and Statistical Manual of Mental Disorder, Fourth Edition (DSM-IV). These questions center around the performance of individual alcohol use disorder (AUD) criteria and the nature of items used to assess them. In this study, we conduct in-depth analyses of interview items used to assess alcohol abuse and dependence.
We conducted Rasch model analyses of responses to 33 items assessing alcohol abuse and dependence criteria in the National Epidemiological Survey on Alcohol and Related Conditions, a nationally representative sample of 34,550 participants. We also examined whether items performed differentially by gender, race/ethnicity, age, education, and time frame of assessment (i.e., past year vs lifetime).
A single latent dimension explained the vast majority of shared variance among the items. Abuse symptoms were not of consistently lower severity than dependence symptoms, and some were consistently prone to differential functioning across subgroups. Items related to tolerance also functioned differentially across subgroups especially in the comparison of past-year symptoms between young adults (ages 18-24) and older adults. Items differed widely in their empirically estimated severity, even when they were intended to assess the same DSM-IV criterion.
The use of Rasch model analyses demonstrated the essential unidimensionality of AUD criteria and the lack of hierarchical ordering between abuse and dependence criteria, as well as potential sources of bias in the abuse diagnosis and the tolerance criterion. Results highlight that the prevalence and even the meaning of AUD criteria can differ substantially depending on the wording of items used to assess them. Implications for assessment of specific DSM criteria and for development of DSM-V are discussed.
关于《精神疾病诊断与统计手册》第四版(DSM-IV)所定义的酒精滥用和酒精依赖的诊断,仍存在诸多问题。这些问题集中在个体酒精使用障碍(AUD)标准的表现以及用于评估这些标准的项目的性质上。在本研究中,我们对用于评估酒精滥用和依赖的访谈项目进行了深入分析。
我们对全国酒精及相关状况流行病学调查中33个评估酒精滥用和依赖标准的项目的回答进行了Rasch模型分析,该调查是一个具有全国代表性的样本,包含34,550名参与者。我们还研究了这些项目在性别、种族/族裔、年龄、教育程度和评估时间框架(即过去一年与终生)方面是否存在差异表现。
一个单一的潜在维度解释了项目之间绝大多数的共同方差。滥用症状的严重程度并不总是低于依赖症状,并且有些症状在不同亚组中始终易于出现差异功能。与耐受性相关的项目在不同亚组中也表现出差异功能,尤其是在比较18 - 24岁的年轻人和老年人过去一年的症状时。即使项目旨在评估相同的DSM-IV标准,它们在经验估计的严重程度上也存在很大差异。
Rasch模型分析的使用证明了AUD标准的基本单维度性以及滥用和依赖标准之间缺乏层次排序,以及滥用诊断和耐受性标准中潜在的偏差来源。结果强调,AUD标准的患病率甚至含义可能会因用于评估它们的项目措辞而有很大差异。讨论了对特定DSM标准评估和DSM-V制定的影响。