Mangin P D, Ludes B P
Institute of Legal Medicine, Strasbourg, France.
Am J Forensic Med Pathol. 1991 Jun;12(2):161-3. doi: 10.1097/00000433-199106000-00014.
Using minisatellite DNA probes that hybridize to a variable number of tandemly repeated loci, an individual-specific DNA fingerprint can be determined. In the case reported here, we succeeded in extracting high-molecular-weight DNA from a 3-month-old fetus discovered during the autopsy of a murdered 28-year-old pregnant woman reported missing 10 days earlier. The results of analysis of restriction-fragment-length polymorphisms showed that all bands present in the fetus's pattern, but absent in the mother's, matched only those of the putative father. Thus, the paternity of the victim's husband was ruled out.
使用能与可变数量串联重复基因座杂交的微卫星DNA探针，可以确定个体特异性的DNA指纹。在本文报道的案例中，我们成功地从一名失踪10天的28岁被谋杀孕妇尸检时发现的3个月大胎儿身上提取了高分子量DNA。限制性片段长度多态性分析结果表明，胎儿图谱中出现但母亲图谱中未出现的所有条带，仅与推定父亲的条带匹配。因此，排除了受害者丈夫的父系关系。
