Shibata Nobuyoshi, Kubota Fumio, Kikuchi Senichiro
Department of Neuropsychiatry, Tatebayashi Kosei Hospital, Gunma, Japan.
Epileptic Disord. 2006 Jun;8(2):131-5.
To clarify the pathogenesis of a typical case of musicogenic epilepsy, we examined interictal spikes using the dipole tracing method (DTM). The patient was a 49-year-old, right-handed Japanese man. He first experienced seizures at the age of 32 years; listening to his favorite piece of music frequently triggered them. His seizure type is partial (often complex, but sometimes simple). An interictal EEG examination revealed many focal spikes in F8 and T4. We estimated equivalent current dipoles (ECDs) using DTM. We performed one-dipole analyses on the peaks of the spikes using an EEG analyzer with a three-layer head model called the scalp-skull-brain (SSB) model. We analyzed the interictal EEG because there were no spikes during the seizure. The ECDs were located in the posterior transverse temporal gyrus. The characteristics in this patient not only bolstered arguments in favor of the role of the right temporal lobe in musicogenic epilepsy, but also showed that transverse temporal gyri, which are included in the auditory area, could play an important role in musicogenic epilepsy.
为阐明一例典型音乐性癫痫的发病机制，我们采用偶极子追踪法（DTM）对发作间期棘波进行了检查。患者为一名49岁、惯用右手的日本男性。他32岁时首次出现癫痫发作；经常听他最喜欢的音乐常引发发作。他的发作类型为部分性发作（常为复杂性发作，但有时为简单性发作）。发作间期脑电图检查显示F8和T4有许多局灶性棘波。我们使用DTM估计等效电流偶极子（ECD）。我们使用一种具有头皮-颅骨-脑（SSB）模型的三层头部模型的脑电图分析仪，对棘波峰值进行单偶极子分析。由于发作期间没有棘波，我们分析了发作间期脑电图。ECD位于颞横回后部。该患者的这些特征不仅支持了右侧颞叶在音乐性癫痫中起作用的观点，还表明听觉区域内的颞横回在音乐性癫痫中可能起重要作用。
