3.0T并行采集腹部动脉高空间分辨率对比增强磁共振血管造影：32例患者的初步经验

High-spatial-resolution contrast-enhanced MR angiography of abdominal arteries with parallel acquisition at 3.0 T: initial experience in 32 patients.

作者信息

Nael Kambiz, Saleh Roya, Lee Margaret, McNamara Thomas, Godinez Sergio R, Laub Gerhard, Finn J Paul, Ruehm Stefan G

机构信息

Department of Radiology, David Geffen School of Medicine, University of California, Los Angeles, 10945 Le Conte Ave., Ste. 3371, Los Angeles, CA 90095, USA.

出版信息

AJR Am J Roentgenol. 2006 Jul;187(1):W77-85. doi: 10.2214/AJR.05.1440.

DOI:10.2214/AJR.05.1440

PMID:16794143

Abstract

OBJECTIVE

The objective of our study was to evaluate an isotropic high-spatial-resolution 3D contrast-enhanced MR angiography (CE-MRA) protocol with high acceleration parallel acquisition at 3.0 T for the display of the abdominal vasculature.

SUBJECTS AND METHODS

Thirty-two consecutive patients (13 men, 19 women; age range, 28-88 years) with suspected abdominal arterial disease underwent abdominal 3D CE-MRA on a 3.0-T MR system, using a high-spatial-resolution (0.7 x 0.82 x 0.8 mm3) 3D gradient-refocused echo (GRE) sequence, integrated with a generalized autocalibrating partially parallel acquisitions (GRAPPA) technique with an acceleration factor of 3. Two vascular radiologists evaluated image quality and the presence and degree of arterial stenoses. Interobserver variability was calculated, using the kappa coefficient. The sensitivity and specificity of the technique were calculated and comparative analysis was performed with those of conventional catheter angiography (in eight patients) as the standard of reference.

RESULTS

The abdominal arterial vasculature was visualized with diagnostic image quality in all subjects. Arterial stenoses were detected in 148 and 142 arterial segments by observer 1 and observer 2, respectively, with good interobserver agreement (kappa = 0.75; 95% confidence interval [CI]: 0.69-0.81). The sensitivity and specificity values for CE-MRA for the detection of significant (> 50%) arterial stenoses were 100% and 96% for observer 1 and 100% and 92% for observer 2, respectively. There was a significant correlation between CE-MRA and conventional angiography (R = 0.96 and 0.93 for observers 1 and 2, respectively) for the assessment of the degree of stenosis.

CONCLUSION

The outlined MR angiography protocol at 3.0 T combined with parallel acquisition technique renders highly reliable and isotropic high-spatial-resolution imaging of the abdominal vasculature.

摘要

目的

本研究的目的是评估一种在3.0 T下具有高加速并行采集的各向同性高空间分辨率三维对比增强磁共振血管造影（CE-MRA）方案，用于显示腹部血管系统。

受试者与方法

32例连续的疑似腹部动脉疾病患者（13例男性，19例女性；年龄范围28 - 88岁）在3.0-T磁共振系统上进行腹部三维CE-MRA检查，使用高空间分辨率（0.7×0.82×0.8 mm³）的三维梯度回聚回波（GRE）序列，并结合加速因子为3的广义自校准部分并行采集（GRAPPA）技术。两名血管放射科医生评估图像质量以及动脉狭窄的存在情况和程度。使用kappa系数计算观察者间的变异性。计算该技术的敏感性和特异性，并与作为参考标准的传统导管血管造影（8例患者）进行比较分析。

结果

所有受试者的腹部动脉血管系统均以具有诊断价值的图像质量显示。观察者1和观察者2分别在148个和142个动脉节段检测到动脉狭窄，观察者间一致性良好（kappa = 0.75；95%置信区间[CI]：0.69 - 0.81）。观察者1检测显著（> 50%）动脉狭窄的CE-MRA敏感性和特异性值分别为100%和96%，观察者2分别为100%和92%。在评估狭窄程度方面，CE-MRA与传统血管造影之间存在显著相关性（观察者1和观察者2的R分别为0.96和0.93）。