Burns Karen C, Boudreau Christian, Panepinto Julie A
Pediatric Hematology/Oncology/Bone Marrow Transplant, Medical College of Wisconsin and The Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, WI, USA.
J Pediatr Hematol Oncol. 2006 Jun;28(6):350-4. doi: 10.1097/00043426-200606000-00006.
Infertility is a devastating side effect of cancer treatment. Advances in fertility research have brought new preservation techniques to the forefront for women. The implication of this research in the field of pediatric oncology has not been reported. The objective of this study was to determine whether female adolescents with a diagnosis of cancer and their parents were interested in trying to preserve fertility. We conducted a cross-sectional survey of female patients, aged 10 to 21 years, and their parents. There were 39 parent/adolescent pair responses, 3 parent-only responses, and 8 adolescent-only responses. We found that adolescents and parents had thought about the future and were interested in research treatments to help preserve fertility, but not willing to postpone cancer therapy. Achieving a state of good health was most important to the adolescent group (P<0.001). There was no statistical difference between attitudes of parents and adolescents. In summary, parents and female adolescents are interested in options to help preserve fertility during cancer treatments, but they are not willing to postpone treatment for this purpose.
不孕症是癌症治疗的一种严重副作用。生育力研究的进展为女性带来了新的生育力保存技术。这项研究在儿科肿瘤学领域的意义尚未见报道。本研究的目的是确定诊断为癌症的女性青少年及其父母是否有兴趣尝试保存生育力。我们对年龄在10至21岁的女性患者及其父母进行了一项横断面调查。有39对父母/青少年的回复、3份仅父母的回复和8份仅青少年的回复。我们发现青少年和父母都考虑过未来，并且对有助于保存生育力的研究性治疗感兴趣，但不愿意推迟癌症治疗。对青少年群体来说，实现健康状态最为重要（P<0.001）。父母和青少年的态度之间没有统计学差异。总之，父母和女性青少年对癌症治疗期间帮助保存生育力的选择感兴趣，但他们不愿意为此目的推迟治疗。
