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储存体:多功能细胞器?

Reservosomes: multipurpose organelles?

作者信息

Cunha-e-Silva Narcisa, Sant'Anna Celso, Pereira Miria Gomes, Porto-Carreiro Isabel, Jeovanio André Luiz, de Souza Wanderley

机构信息

Instituto de Biofisica Carlos Chagas Filho, CCS, Bloco G, subsolo, Universidade Federal do Rio de Janeiro, Cidade Universitaria, Rio de Janeiro, RJ, CEP 21949-900, Brazil.

出版信息

Parasitol Res. 2006 Sep;99(4):325-7. doi: 10.1007/s00436-006-0190-3. Epub 2006 Jun 23.

DOI:10.1007/s00436-006-0190-3
PMID:16794853
Abstract

Reservosomes are endocytic organelles from Trypanosoma cruzi epimastigotes that store proteins and lipids for future use. The lack of molecular markers for the compartments of this parasite makes it difficult to clarify all reservosome functions, as they present characteristics of pre-lysosomes, lysosomes and recycling compartments.

摘要

储存体是克氏锥虫前鞭毛体的内吞细胞器,用于储存蛋白质和脂质以供未来使用。由于这种寄生虫的细胞器缺乏分子标记,因此难以阐明储存体的所有功能,因为它们具有前溶酶体、溶酶体和再循环细胞器的特征。

相似文献

1
Reservosomes: multipurpose organelles?储存体:多功能细胞器?
Parasitol Res. 2006 Sep;99(4):325-7. doi: 10.1007/s00436-006-0190-3. Epub 2006 Jun 23.
2
Biogenesis of the reservosomes of Trypanosoma cruzi.克氏锥虫储存体的生物发生
Microsc Microanal. 2004 Oct;10(5):637-46. doi: 10.1017/S1431927604040863.
3
The reservosome of Trypanosoma cruzi epimastigotes: an organelle of the endocytic pathway with a role on metacyclogenesis.克氏锥虫上鞭毛体的储存体:一种内吞途径的细胞器,在循环后期发育中起作用。
Mem Inst Oswaldo Cruz. 1999;94 Suppl 1:139-41. doi: 10.1590/s0074-02761999000700015.
4
Reservosome: an endocytic compartment in epimastigote forms of the protozoan Trypanosoma cruzi (Kinetoplastida: Trypanosomatidae). Correlation between endocytosis of nutrients and cell differentiation.贮存体:原生动物克氏锥虫(动基体目:锥虫科)上鞭毛体形式中的一种内吞区室。营养物质内吞与细胞分化之间的相关性。
Parasitology. 2004 Oct;129(Pt 4):431-8. doi: 10.1017/s0031182004005797.
5
Lysosome-like compartments of Trypanosoma cruzi trypomastigotes may originate directly from epimastigote reservosomes.克氏锥虫锥鞭毛体的类溶酶体区室可能直接起源于上鞭毛体储存小体。
Parasitology. 2017 May;144(6):841-850. doi: 10.1017/S0031182016002602. Epub 2017 Jan 12.
6
All Trypanosoma cruzi developmental forms present lysosome-related organelles.所有克氏锥虫发育形态均呈现出溶酶体相关细胞器。
Histochem Cell Biol. 2008 Dec;130(6):1187-98. doi: 10.1007/s00418-008-0486-8. Epub 2008 Aug 12.
7
Identification of a large pre-lysosomal compartment in the pathogenic protozoon Trypanosoma cruzi.在致病性原生动物克氏锥虫中鉴定出一个大型前溶酶体区室。
J Cell Sci. 1992 May;102 ( Pt 1):157-67. doi: 10.1242/jcs.102.1.157.
8
mAb CZP-315.D9: an antirecombinant cruzipain monoclonal antibody that specifically labels the reservosomes of Trypanosoma cruzi epimastigotes.单抗 CZP-315.D9:一种抗重组克氏锥虫 cruzipain 的单克隆抗体,可特异性标记克氏锥虫滋养体的内寄生物。
Biomed Res Int. 2014;2014:714749. doi: 10.1155/2014/714749. Epub 2014 Jan 23.
9
An ultrastructure study of the in vitro effects of L-leucine methyl ester and ammonium chloride on Trypanosoma cruzi epimastigotes.L-亮氨酸甲酯和氯化铵对克氏锥虫前鞭毛体体外作用的超微结构研究
Parasitol Res. 1996;82(4):285-90. doi: 10.1007/s004360050115.
10
Tridimensional Electron Microscopy Analysis of the Early Endosomes and Endocytic Traffic in Trypanosoma cruzi Epimastigotes.克氏锥虫前鞭毛体早期内体及内吞运输的三维电子显微镜分析
Protist. 2018 Dec;169(6):887-910. doi: 10.1016/j.protis.2018.09.004. Epub 2018 Sep 29.

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Characterization of the RNA-Binding Protein TcSgn1 in .疟原虫中RNA结合蛋白TcSgn1的特性分析 。(原文句子不完整,推测补充了这部分以使翻译更合理)

本文引用的文献

1
Role for a P-type H+-ATPase in the acidification of the endocytic pathway of Trypanosoma cruzi.P型H⁺-ATP酶在克氏锥虫内吞途径酸化中的作用。
Biochem J. 2005 Dec 15;392(Pt 3):467-74. doi: 10.1042/BJ20051319.
2
Biogenesis of the reservosomes of Trypanosoma cruzi.克氏锥虫储存体的生物发生
Microsc Microanal. 2004 Oct;10(5):637-46. doi: 10.1017/S1431927604040863.
3
Trypanosoma cruzi: TcRAB7 protein is localized at the Golgi apparatus in epimastigotes.克氏锥虫:TcRAB7蛋白定位于无鞭毛体的高尔基体。
Microorganisms. 2021 May 2;9(5):986. doi: 10.3390/microorganisms9050986.
4
If host is refractory, insistent parasite goes berserk: Trypanosomatid Blastocrithidia raabei in the dock bug Coreus marginatus.如果宿主有抗性,固执的寄生虫就会变得疯狂: dock bug Coreus marginatus 中的锥虫 Blastocrithidia raabei。
PLoS One. 2020 Jan 16;15(1):e0227832. doi: 10.1371/journal.pone.0227832. eCollection 2020.
5
Lysosome assembly and disassembly changes endocytosis rate through the Leishmania cell cycle.溶酶体的组装和拆解通过利什曼原虫的细胞周期改变内吞作用的速率。
Microbiologyopen. 2020 Feb;9(2):e969. doi: 10.1002/mbo3.969. Epub 2019 Nov 19.
6
Knockout of the gamma subunit of the AP-1 adaptor complex in the human parasite Trypanosoma cruzi impairs infectivity and differentiation and prevents the maturation and targeting of the major protease cruzipain.在人类寄生虫克氏锥虫中敲除衔接蛋白复合体AP-1的γ亚基会损害其感染性和分化能力,并阻止主要蛋白酶克氏锥虫蛋白酶的成熟和靶向作用。
PLoS One. 2017 Jul 31;12(7):e0179615. doi: 10.1371/journal.pone.0179615. eCollection 2017.
7
Interactions between 4-aminoquinoline and heme: Promising mechanism against Trypanosoma cruzi.4-氨基喹啉与血红素之间的相互作用:对抗克氏锥虫的潜在机制。
Int J Parasitol Drugs Drug Resist. 2016 Dec;6(3):154-164. doi: 10.1016/j.ijpddr.2016.07.001. Epub 2016 Jul 14.
8
RNA-binding proteins related to stress response and differentiation in protozoa.原生动物中与应激反应和分化相关的RNA结合蛋白
World J Biol Chem. 2016 Feb 26;7(1):78-87. doi: 10.4331/wjbc.v7.i1.78.
9
Autophagy in trypanosomatids.原虫中的自噬作用。
Cells. 2012 Jul 27;1(3):346-71. doi: 10.3390/cells1030346.
10
mAb CZP-315.D9: an antirecombinant cruzipain monoclonal antibody that specifically labels the reservosomes of Trypanosoma cruzi epimastigotes.单抗 CZP-315.D9:一种抗重组克氏锥虫 cruzipain 的单克隆抗体,可特异性标记克氏锥虫滋养体的内寄生物。
Biomed Res Int. 2014;2014:714749. doi: 10.1155/2014/714749. Epub 2014 Jan 23.
Biochem Biophys Res Commun. 2004 Aug 20;321(2):397-402. doi: 10.1016/j.bbrc.2004.06.159.
4
Isolation and characterization of a reservosome fraction from Trypanosoma cruzi.克氏锥虫储存体组分的分离与鉴定
FEMS Microbiol Lett. 2002 Aug 27;214(1):7-12. doi: 10.1111/j.1574-6968.2002.tb11317.x.
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Rab proteins as membrane organizers.作为膜组织者的Rab蛋白。
Nat Rev Mol Cell Biol. 2001 Feb;2(2):107-17. doi: 10.1038/35052055.
6
Characterization of a Rab11 homologue in Trypanosoma cruzi.克氏锥虫中Rab11同源物的鉴定
Gene. 2000 Feb 8;243(1-2):179-85. doi: 10.1016/s0378-1119(99)00480-1.
7
Cytoplasmic organelles of trypanosomatids: a cytochemical and stereological study.锥虫的细胞质细胞器:细胞化学和体视学研究
J Submicrosc Cytol Pathol. 1988 Apr;20(2):349-61.
8
A stereological study of the differentiation process in Trypanosoma cruzi.克氏锥虫分化过程的体视学研究。
Parasitol Res. 1989;75(7):522-7. doi: 10.1007/BF00931160.
9
Cysteine proteinase in Trypanosoma cruzi: immunocytochemical localization and involvement in parasite-host cell interaction.克氏锥虫中的半胱氨酸蛋白酶:免疫细胞化学定位及其在寄生虫与宿主细胞相互作用中的作用
J Cell Sci. 1990 Jul;96 ( Pt 3):485-90. doi: 10.1242/jcs.96.3.485.
10
Ultrastructural patterns of the flagellar axoneme in the non-motile part of the mole-cricket sperm.蝼蛄精子非运动部分鞭毛轴丝的超微结构模式。
Biol Cell. 1990;70(1-2):19-26. doi: 10.1016/0248-4900(90)90356-8.