Chauveau M, Bassez S, Tra S, Scherrer B
Department of Physiology, Cochin Hospital, Paris, France.
Vasa. 2006 May;35(2):59-66. doi: 10.1024/0301-1526.35.2.59.
The mechanical properties of human veins remain incompletely known. However they play an important part in number of physiological and pathological situations, as hemodynamic adjustment to orthostasis, deep venous thrombosis (DVP) and chronic venous insufficiency (CVI). The aim of the study was to describe the pressure/volume (area) relationship of some important conduit veins of the human's lower limb.
We investigated the area/pressure relationship of thefemoral vein (FV) at mid thigh, the great saphenous vein (GSV) at lower third of the leg, and a deep leg vein (DLV), either the peroneal or posterior tibial vein, in fifteen healthy young men. The cross section areas were measured with B-mode ultrasound while various positive and negative venous pressures were generated by body's tilting.
Over the range of pressures investigated, the area/pressure relationship was roughly linear, the classical sigmoid relation did not emerge from our data. The relative compliance of FV, GSV and DLV was 0.0312, 0.0118, and 0.0147 mmHg(-1), respectively.
The relative compliance of FV is more than two times higher than the relative compliance of both the DLV and the GSV.
人类静脉的力学特性仍未完全明确。然而，它们在许多生理和病理情况下发挥着重要作用，如对直立姿势的血流动力学调节、深静脉血栓形成（DVT）和慢性静脉功能不全（CVI）。本研究的目的是描述人类下肢一些重要的传导静脉的压力/容积（面积）关系。
我们在15名健康年轻男性中，研究了大腿中部股静脉（FV）、小腿下三分之一处大隐静脉（GSV）以及一条小腿深部静脉（DLV，腓静脉或胫后静脉）的面积/压力关系。通过身体倾斜产生各种正负静脉压力时，用B型超声测量横截面面积。
在所研究的压力范围内，面积/压力关系大致呈线性，我们的数据未呈现出经典的S形关系。FV、GSV和DLV的相对顺应性分别为0.0312、0.0118和0.0147 mmHg⁻¹。
FV的相对顺应性比DLV和GSV的相对顺应性高出两倍多。
