Srivastava A K, Gupta B N, Mathur A K, Mathur N, Mahendra P N, Bharti R S
Epidemiology Division, Industrial Toxicology Research Centre, Luchnow, India.
Hum Exp Toxicol. 1991 Jul;10(4):279-83. doi: 10.1177/096032719101000407.
Clinical, haematological and biochemical studies of 34 subjects, occupationally exposed to different types of pesticides, were conducted. The findings have been compared with those observed in 14 control subjects. Inhibition of cholinesterase activity was observed in the exposed group. Serum alkaline phosphatase was also found to be raised. Radiological examination revealed pneumonitic patches in the chest skiagrams of three exposed subjects. Paraesthesia with hyporeflexia was also found in 8.8% of exposed subjects. The findings suggest that exposure to multiple pesticides over many years affects the normal functioning of different organ systems and may produce characteristic clinical effects.
对34名职业性接触不同类型农药的受试者进行了临床、血液学和生化研究。将研究结果与14名对照受试者的观察结果进行了比较。在暴露组中观察到胆碱酯酶活性受到抑制。还发现血清碱性磷酸酶升高。放射学检查显示，3名暴露受试者的胸部X光片上有肺炎性斑片。8.8%的暴露受试者还出现了感觉异常伴反射减退。研究结果表明，多年接触多种农药会影响不同器官系统的正常功能，并可能产生特征性的临床效应。
