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Activity of rituximab monotherapy in refractory splenic marginal zone lymphoma complicated with autoimmune hemolytic anemia.

作者信息

Fabbri Alberto, Gozzetti Alessandro, Lazzi Stefano, Lenoci Mariapia, D'Amuri Alessandro, Leoncini Lorenzo, Lauria Francesco

机构信息

Division of Hematology and Transplants, Policlinico S. Maria alle Scotte, and University of Siena, Italy.

出版信息

Clin Lymphoma Myeloma. 2006 May;6(6):496-9. doi: 10.3816/CLM.2006.n.033.

DOI:10.3816/CLM.2006.n.033
PMID:16796783
Abstract

We describe the case of a 61-year-old patient with refractory splenic marginal zone lymphoma and secondary autoimmune hemolytic anemia, both successfully treated with rituximab. This case demonstrates that rituximab monotherapy might also be a valid therapeutic approach in marginal zone lymphoma and autoimmune hemolytic anemia after failure of first-line treatment. Maintenance therapy, although expensive, could be useful to improve event-free survival in patients with unfavorable clinical behavior.

摘要

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Clin Lymphoma Myeloma. 2006 May;6(6):496-9. doi: 10.3816/CLM.2006.n.033.
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