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上皮细胞的红外显微光谱研究

Infrared micro-spectroscopic studies of epithelial cells.

作者信息

Romeo Melissa, Mohlenhoff Brian, Jennings Michael, Diem Max

机构信息

Department of Chemistry and Biochemistry, City University of New York, Hunter College, New York, NY 10021, USA.

出版信息

Biochim Biophys Acta. 2006 Jul;1758(7):915-22. doi: 10.1016/j.bbamem.2006.05.010. Epub 2006 May 19.

Abstract

We report results from a study of human and canine mucosal cells, investigated by infrared micro-spectroscopy, and analyzed by methods of multivariate statistics. We demonstrate that the infrared spectra of individual cells are sensitive to the stage of maturation, and that a distinction between healthy and diseased cells will be possible. Since this report is written for an audience not familiar with infrared micro-spectroscopy, a short introduction into this field is presented along with a summary of principal component analysis.

摘要

我们报告了一项关于人类和犬类黏膜细胞的研究结果,该研究采用红外显微光谱法进行调查,并通过多元统计方法进行分析。我们证明,单个细胞的红外光谱对成熟阶段敏感,并且有可能区分健康细胞和患病细胞。由于本报告是为不熟悉红外显微光谱法的读者撰写的,因此在介绍主成分分析总结的同时,对该领域进行了简要介绍。

相似文献

1
Infrared micro-spectroscopic studies of epithelial cells.上皮细胞的红外显微光谱研究
Biochim Biophys Acta. 2006 Jul;1758(7):915-22. doi: 10.1016/j.bbamem.2006.05.010. Epub 2006 May 19.

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