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2
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[Size, form and arrangement of keratinizing mucous membrane cells].[角化黏膜细胞的大小、形态及排列]
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Shining a new light into molecular workings.为分子运作机制带来新的启示。
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本文引用的文献

1
Infrared micro-spectroscopy of human cells: Causes for the spectral variance of oral mucosa (buccal) cells.人体细胞的红外显微光谱学：口腔黏膜（颊部）细胞光谱变化的原因
Vib Spectrosc. 2006 Oct 18;42(1):9-14. doi: 10.1016/j.vibspec.2006.04.009.
2
Infrared spectral imaging of lymph nodes: Strategies for analysis and artifact reduction.淋巴结的红外光谱成像：分析策略与伪影减少
Vib Spectrosc. 2005 Jul 29;38(1-2):115-119. doi: 10.1016/j.vibspec.2005.03.009.
3
Delimitation of squamous cell cervical carcinoma using infrared microspectroscopic imaging.利用红外显微光谱成像技术对宫颈鳞状细胞癌进行界定
Anal Bioanal Chem. 2006 Jan;384(1):145-54. doi: 10.1007/s00216-005-0124-4. Epub 2005 Dec 3.
4
Mie-type scattering and non-Beer-Lambert absorption behavior of human cells in infrared microspectroscopy.红外光谱学中人体细胞的米氏型散射和非比尔-朗伯吸收行为
Biophys J. 2005 May;88(5):3635-40. doi: 10.1529/biophysj.104.057950. Epub 2005 Mar 4.
5
Analysis of human brain tissue, brain tumors and tumor cells by infrared spectroscopic mapping.通过红外光谱成像分析人类脑组织、脑肿瘤及肿瘤细胞。
Analyst. 2004 Oct;129(10):921-5. doi: 10.1039/b408934k. Epub 2004 Aug 4.
6
Fourier transform infrared (FTIR) spectral mapping of the cervical transformation zone, and dysplastic squamous epithelium.宫颈转化区及发育异常鳞状上皮的傅里叶变换红外（FTIR）光谱成像。
Gynecol Oncol. 2004 Apr;93(1):59-68. doi: 10.1016/j.ygyno.2003.12.028.
7
Imaging of colorectal adenocarcinoma using FT-IR microspectroscopy and cluster analysis.使用傅里叶变换红外光谱显微镜和聚类分析对结肠直肠癌进行成像。
Biochim Biophys Acta. 2004 Mar 2;1688(2):176-86. doi: 10.1016/j.bbadis.2003.12.006.
8
FTIR microspectroscopic study of cell types and potential confounding variables in screening for cervical malignancies.傅里叶变换红外光谱显微技术在宫颈恶性肿瘤筛查中对细胞类型及潜在混杂变量的研究
Biospectroscopy. 1998;4(2):75-91. doi: 10.1002/(SICI)1520-6343(1998)4:2%3C75::AID-BSPY1%3E3.0.CO;2-R.
9
Infrared spectroscopy of human tissue. IV. Detection of dysplastic and neoplastic changes of human cervical tissue via infrared microscopy.人体组织的红外光谱学。IV. 通过红外显微镜检测人宫颈组织的发育异常和肿瘤性变化。
Cell Mol Biol (Noisy-le-grand). 1998 Feb;44(1):219-29.
10
Infrared spectroscopy of human tissue. II. A comparative study of spectra of biopsies of cervical squamous epithelium and of exfoliated cervical cells.人体组织的红外光谱学。II. 宫颈鳞状上皮活检组织与宫颈脱落细胞光谱的比较研究。
Biospectroscopy. 1998;4(1):55-9. doi: 10.1002/(SICI)1520-6343(1998)4:1%3C55::AID-BSPY6%3E3.0.CO;2-R.

上皮细胞的红外显微光谱研究

Infrared micro-spectroscopic studies of epithelial cells.

作者信息

Romeo Melissa, Mohlenhoff Brian, Jennings Michael, Diem Max

机构信息

Department of Chemistry and Biochemistry, City University of New York, Hunter College, New York, NY 10021, USA.

出版信息

Biochim Biophys Acta. 2006 Jul;1758(7):915-22. doi: 10.1016/j.bbamem.2006.05.010. Epub 2006 May 19.

DOI:10.1016/j.bbamem.2006.05.010
PMID:16797481
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2732433/
Abstract

We report results from a study of human and canine mucosal cells, investigated by infrared micro-spectroscopy, and analyzed by methods of multivariate statistics. We demonstrate that the infrared spectra of individual cells are sensitive to the stage of maturation, and that a distinction between healthy and diseased cells will be possible. Since this report is written for an audience not familiar with infrared micro-spectroscopy, a short introduction into this field is presented along with a summary of principal component analysis.

摘要

我们报告了一项关于人类和犬类黏膜细胞的研究结果，该研究采用红外显微光谱法进行调查，并通过多元统计方法进行分析。我们证明，单个细胞的红外光谱对成熟阶段敏感，并且有可能区分健康细胞和患病细胞。由于本报告是为不熟悉红外显微光谱法的读者撰写的，因此在介绍主成分分析总结的同时，对该领域进行了简要介绍。