André Josette, Lateur Nadine
Department of Dermatology, CHU Saint-Pierre, Brugmann, HUDERF, 129, Bd de Waterloo, B-1000 Brussels, Free University of Brussels, Belgium.
Dermatol Clin. 2006 Jul;24(3):329-39. doi: 10.1016/j.det.2006.03.012.
Nail pigmentation is defined by the presence of melanin in the nail plate. It most frequently has the appearance of a longitudinal pigmented band, called longitudinal mel-anonychia (LM). LM is an important aspect of ungual pathology because it can be the first sign of nail apparatus melanoma. The aim of this article is to help distinguish those types of melanonychia that are worrisome and should lead to biopsy from those that are reasonably reassuring and need only be followed clinically. Histology, differential diagnosis, and biopsy techniques also are considered.
甲色素沉着是由甲板中黑色素的存在所定义的。它最常见的表现为纵向色素带,称为纵向黑甲(LM)。LM是甲病学的一个重要方面,因为它可能是甲器黑色素瘤的首个迹象。本文的目的是帮助区分那些令人担忧并应进行活检的黑甲类型与那些相对放心且仅需临床随访的类型。同时也会考虑组织学、鉴别诊断和活检技术。