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早期甲下黑素沉着:良性表现还是隐匿性恶性肿瘤?一例甲下黑色素瘤病例报告

Incipient Melanonychia: Benign Finding or Occult Malignancy? A Case Report of Subungual Melanoma.

作者信息

Quiroz Alfaro Alejandro J, Greiffenstein Juliana, Herrera Ortiz Andrés Felipe, Dussan Tovar Catalina A, Saldarriaga Santamaría Sara, Cifuentes Burbano Jaqueline, García Nataly, Rodríguez Díaz Maria C, Sierra Molina Susana M, Jiménez Calfat Guillermo

机构信息

Medicine and Health Sciences, Universidad Colegio Mayor de Nuestra Señora del Rosario, Bogotá D.C., COL.

Facultad de Medicina, Universidad Pontificia Bolivariana, Medellín, COL.

出版信息

Cureus. 2023 Jan 27;15(1):e34292. doi: 10.7759/cureus.34292. eCollection 2023 Jan.

Abstract

Subungual melanomas are rare neoplasms that tend to debut as longitudinal melanonychia. They are primarily found in patients over 60 years of age and are usually diagnosed late, representing a diagnostic challenge. We present a case report of a 59-year-old female Hispanic patient who initially presented with melanonychia and was eventually diagnosed with subungual melanoma in situ. She was surgically treated and, after three months, remained healthy. Relevant risk factors, clinical and onychoscopic findings, diagnostic criteria, and treatment options are also discussed. Since many benign entities present similarly, high clinical suspicion is critical for diagnosing this entity.

摘要

甲下黑色素瘤是一种罕见的肿瘤,通常以纵向黑甲的形式出现。它们主要见于60岁以上的患者,且通常诊断较晚,构成了一项诊断挑战。我们报告一例59岁西班牙裔女性患者,该患者最初表现为黑甲,最终被诊断为原位甲下黑色素瘤。她接受了手术治疗,三个月后仍保持健康。文中还讨论了相关危险因素、临床和甲下镜检查结果、诊断标准及治疗选择。由于许多良性病变表现相似,高度的临床怀疑对于诊断该疾病至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f97/9883383/b544b2e3fba9/cureus-0015-00000034292-i01.jpg

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