Singh Varinder
Lady Hardinge Medical College and Assoc Kalawati Saran Children's Hospital, Bangla Sahib Marg, New Delhi 110001, India.
Paediatr Respir Rev. 2006;7 Suppl 1:S132-5. doi: 10.1016/j.prrv.2006.04.222. Epub 2006 Jun 6.
Childhood tuberculosis poses great challenges to the public health manager as well as the pediatrician. While mycobacterial detection and isolation remain the gold standard but has a poor sensitivity for several reasons. The diagnosis of the disease is often based on indirect methods like PPD positivity, radiological features and history of contact. Serology and PCR based diagnostic methods have failed to help a clinician working at the peripheral level. The review shares and discusses the place of the various tests in the diagnosis of tuberculosis. WHO has been propagating the use of intermittent supervised treatment for all cases including children. We discuss the concerns of the pediatricians and share our experience on this therapy.
儿童结核病给公共卫生管理人员和儿科医生都带来了巨大挑战。虽然分枝杆菌检测和分离仍是金标准，但由于多种原因其敏感性较差。该疾病的诊断通常基于如结核菌素试验阳性、放射学特征和接触史等间接方法。血清学和基于聚合酶链反应的诊断方法未能帮助基层临床医生。本综述分享并讨论了各种检测在结核病诊断中的地位。世界卫生组织一直在推广对包括儿童在内的所有病例采用间歇督导治疗。我们讨论了儿科医生的担忧，并分享了我们在这种治疗方法上的经验。
