中国成年人青光眼的患病率及临床特征：一项基于广州荔湾区人群的研究

Prevalence and clinical characteristics of glaucoma in adult Chinese: a population-based study in Liwan District, Guangzhou.

作者信息

He Mingguang, Foster Paul J, Ge Jian, Huang Wenyong, Zheng Yingfeng, Friedman David S, Lee Pak Sang, Khaw Peng T

机构信息

Institute of Ophthalmology, University College London, and Glaucoma Research Unit, Moorfields Eye Hospital, United Kingdom.

出版信息

Invest Ophthalmol Vis Sci. 2006 Jul;47(7):2782-8. doi: 10.1167/iovs.06-0051.

DOI:10.1167/iovs.06-0051

PMID:16799014

Abstract

PURPOSE

To assess the prevalence and mechanism of glaucoma in adults living in an urban area of southern China.

METHODS

Random clustering sampling was used to identify adults aged 50 years and over in Liwan District, Guangzhou. Glaucoma was diagnosed with the ISGEO (International Society of Geographical and Epidemiological Ophthalmology) classification scheme. All subjects underwent gonioscopy.

RESULTS

In the study, 1504 subjects (75.3% participation rate) were examined, with a crude prevalence of all glaucoma of 3.8% (95% confidence interval [CI], 2.8%-4.8%). Primary open-angle glaucoma (POAG) was found in 2.1% (95% CI, 1.4%-2.8%) and primary angle-closure glaucoma (PACG) in 1.5% (95% CI, 0.8%-2.1%). The prevalence of all glaucoma was significantly higher in older people and men.

CONCLUSIONS

POAG was more common than PACG in this southern Chinese population, with rates similar to those reported in Chinese Singaporeans. The age-adjusted rate of POAG was similar to that found in European-derived populations, but PACG was more common among Chinese, indicating that there is a large burden of glaucoma in the Chinese people.

摘要

目的

评估中国南方城市地区成年人青光眼的患病率及发病机制。

方法

采用随机整群抽样法，在广州荔湾区选取50岁及以上的成年人。青光眼的诊断采用国际地理与流行病学眼科学会（ISGEO）分类方案。所有受试者均接受前房角镜检查。

结果

本研究共检查了1504名受试者（参与率为75.3%），青光眼的总体患病率为3.8%（95%置信区间[CI]，2.8%-4.8%）。原发性开角型青光眼（POAG）的患病率为2.1%（95%CI，1.4%-2.8%），原发性闭角型青光眼（PACG）的患病率为1.5%（95%CI，0.8%-2.1%）。青光眼的总体患病率在老年人和男性中显著更高。