Herranz Amo Felipe, Diéz Cordero José María, Cabello Benavente Ramiro
Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, España.
Arch Esp Urol. 2006 May;59(4):385-96.
To analyze the various techniques of transrectal ultrasound guided biopsy of the prostate described in the literature, as well as the anesthesia modalities for its performance. The diagnostic yield of the classic sextant biopsy, described 16 years ago and considered the standard technique ever since, has been overcome by the extended biopsy techniques (greater number of cores from more prostatic areas in each biopsy). Although their intra-study yield is better than sextant biopsy, the scarce randomized studies have not demonstrated a statistically significant improvement. These new techniques of extended biopsy significantly increase the rate of minor complications, not the major. It has not been demonstrated an increase in either the perception of pain or the diagnosis of non-significant tumors. Any anesthetic technique employed diminishes significantly the perception of pain by the patient. The periprostatic nerve blockage with infiltration of lidocaine is better than the rest of the techniques. The best technique of infiltration and the most effective lidocaine dose are to be defined yet. These techniques do not increase complications and only prolong the procedure briefly.
分析文献中描述的经直肠超声引导下前列腺穿刺活检的各种技术及其操作时的麻醉方式。经典的六分区活检技术于16年前被描述,并自那时起一直被视为标准技术,但其诊断率已被扩展活检技术(每次活检从更多前列腺区域获取更多的组织芯)所超越。尽管它们在研究中的取材率优于六分区活检,但少数随机研究并未显示出统计学上的显著改善。这些扩展活检的新技术显著增加了轻微并发症的发生率,而非严重并发症。尚未证实疼痛感知或无意义肿瘤的诊断有所增加。所采用的任何麻醉技术都能显著减轻患者的疼痛感知。利多卡因浸润的前列腺周围神经阻滞优于其他技术。浸润的最佳技术和利多卡因的最有效剂量仍有待确定。这些技术不会增加并发症,只会使操作时间稍有延长。