Hampson Neil B, Scott Karen L
Section of Pulmonary and Critical Care Medicine, Virginia Mason Medical Center, Seattle, Washington 98101, USA.
Respir Care. 2006 Jul;51(7):758-60.
Though smokers are known to have elevated blood carboxyhemoglobin (COHb), due to inhalation of carbon monoxide (CO) in cigarette smoke, limited data exist regarding COHb levels in nonsmokers exposed to secondhand smoke.
COHb was measured using a new noninvasive pulse CO-oximeter (Rad-57, Masimo, Irvine, California) in 38 subjects entering a bingo hall where smoking was allowed, then again as they exited 3 hours later.
The mean +/- SD baseline COHb for the entire group was 3.3 +/- 1.8%, for the 23 nonsmokers it was 2.2 +/- 0.7%, and for the 15 smokers it was 4.9 +/- 1.9%. The nonsmokers' mean COHb was unchanged, at 2.2 +/- 0.8%, whereas the smokers' mean COHb fell to 3.2 +/- 1.9%.
The nonsmokers were not significantly exposed to CO from secondhand smoke in the setting we tested. The smokers probably consumed fewer cigarettes while playing bingo than they did prior to arrival. The Rad-57 pulse CO-oximeter is easy to use in the ambulatory setting.
尽管已知吸烟者因吸入香烟烟雾中的一氧化碳(CO)而导致血液中碳氧血红蛋白(COHb)水平升高,但关于接触二手烟的非吸烟者的COHb水平的数据有限。
使用一种新型无创脉搏碳氧血红蛋白测定仪(Rad-57,Masimo公司,加利福尼亚州欧文市)对38名进入允许吸烟的宾果游戏厅的受试者进行COHb测量,3小时后他们离开时再次测量。
整个组的平均±标准差基线COHb为3.3±1.8%,23名非吸烟者为2.2±0.7%,15名吸烟者为4.9±1.9%。非吸烟者的平均COHb保持不变,为2.2±0.8%,而吸烟者的平均COHb降至3.2±1.9%。
在我们测试的环境中,非吸烟者未明显接触到二手烟中的CO。吸烟者在玩宾果游戏时可能比到达之前吸的香烟更少。Rad-57脉搏碳氧血红蛋白测定仪在门诊环境中易于使用。