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使用氟化物涂剂治疗颈部牙本质过敏:一项随机临床研究。

Treating cervical dentin hypersensitivity with fluoride varnish: a randomized clinical study.

作者信息

Ritter André V, de L Dias Walter, Miguez Patrícia, Caplan Daniel J, Swift Edward J

机构信息

Department of Operative Dentistry, The University of North Carolina at Chapel Hill, School of Dentistry, 441 Brauer Hall, CB #7450, 27599-7450, USA.

出版信息

J Am Dent Assoc. 2006 Jul;137(7):1013-20; quiz 1029. doi: 10.14219/jada.archive.2006.0324.

Abstract

BACKGROUND

This subject-blind randomized clinical trial tested the efficacy of a new 5 percent sodium fluoride varnish (AllSolutions Fluoride Varnish, Dentsply Professional, York, Pa.) for treatment of cervical dentin hypersensitivity. The authors also compared the test varnish with a control fluoride varnish (Duraphat, Colgate Oral Pharmaceuticals, New York City).

METHODS

The study involved application of the test or control varnish to 19 subjects (59 teeth) with tooth sensitivity. The authors applied each product once to each tooth, following manufacturers' instructions. They used a visual analog scale (VAS) to assess subjects' responses to compressed air and ice stimuli at six weeks before baseline, at baseline and at two, eight and 24 weeks after treatment.

RESULTS

Mean VAS scores for teeth receiving the test varnish dropped from 34.9 (air) and 68.0 (ice) at baseline to 26.3 (air) and 54.7 (ice) at two weeks after treatment. Mean scores at 24 weeks were 20.6 (air) and 34.8 (ice), representing statistically significant differences from baseline values. For the control varnish, mean VAS scores dropped from 36.9 (air) and 64.2 (ice) at baseline to 32.9 (air) and 47.2 (ice) at two weeks, and to 20.8 (air) and 40.3 (ice) at 24 weeks. The authors analyzed the data for statistical significance, accounting for clustering of teeth within subjects.

CONCLUSION AND CLINICAL IMPLICATIONS

The test varnish was effective in reducing cervical dentin hypersensitivity. However, the efficacy was not significantly different from that of the control varnish.

摘要

背景

这项单盲随机临床试验测试了一种新型5%氟化钠清漆(全解决方案氟化物清漆,登士柏专业产品,宾夕法尼亚州约克)治疗颈部牙本质过敏的疗效。作者还将测试清漆与对照氟化物清漆(Duraphat,高露洁口腔制药公司,纽约市)进行了比较。

方法

该研究涉及将测试或对照清漆应用于19名有牙齿敏感症状的受试者(59颗牙齿)。作者按照制造商的说明,对每颗牙齿各使用一次每种产品。他们使用视觉模拟量表(VAS)在基线前六周、基线时以及治疗后两周、八周和24周评估受试者对压缩空气和冰刺激的反应。

结果

接受测试清漆的牙齿的平均VAS评分从基线时的34.9(空气)和68.0(冰)降至治疗后两周时的26.3(空气)和54.7(冰)。24周时的平均评分分别为20.6(空气)和34.8(冰),与基线值相比有统计学显著差异。对于对照清漆,平均VAS评分从基线时的36.9(空气)和64.2(冰)降至两周时的32.9(空气)和47.2(冰),并在24周时降至20.8(空气)和40.3(冰)。作者分析了数据的统计学显著性,考虑了受试者牙齿的聚集情况。

结论及临床意义

测试清漆在降低颈部牙本质过敏方面有效。然而,其疗效与对照清漆相比无显著差异。

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