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[运动对预防冠心病的重要性——生理和病理生理方面]

[The importance of sports for the prevention of coronary heart disease--physiological and pathophysiological aspects].

作者信息

Rost R

机构信息

Institut für Kreislaufforschung und Sportmedizin, Deutsche Sporthochschule Köln.

出版信息

Herz. 1991 Aug;16(4):210-21.

PMID:1680781
Abstract

For the application of physical conditioning in the prevention of coronary heart disease to be meaningful, account must be taken of physiological and pathophysiological baselines. Physical activity is associated with an increase in metabolic rate, and the prophylactic effect of exercise is due mainly to metabolic effects and not, as commonly thought, to hemodynamic factors. Raising the metabolic rate has a positive effect on risk factors which--with the exception of smoking--are largely metabolic. For this reason, the physiological aspects of the release of energy and its increase under physical exercise are described. Of decisive importance for prophylaxis is not so much the nature of the exercise--for example endurance training in particular--as the overall extent of physical exercise, and the resulting energy consumption. The hemodynamic effect of physical activity, in particular the optimization of cardiovascular function, is of importance not so much for primary preventive reasons as for reducing the oxygen requirement of the myocardium--a secondary preventive measure. For producing a cardiovascular training effect, forms of exercise performed close to the aerobic-anaerobic threshold (AAT) are optimal. A common mistake is to assume that the training effect achieved under physiological conditions can simply be extrapolated to the pathophysiological situation. Exercise workloads that are below the aerobic-anaerobic threshold fail to produce a training effect. Here, the major aim must be to achieve metabolic, coordinative and motivational effects. If the physiological responses to exercise, in particular heart rate, are modified by pathophysiological or pharmacological mechanisms, other, in particular respiratory and metabolic parameters should be used as regulators of training. Such parameters are considered in detail.

摘要

为使体能训练在预防冠心病方面具有意义,必须考虑生理和病理生理基线。体力活动与代谢率增加相关,运动的预防作用主要归因于代谢效应,而非如通常所认为的血流动力学因素。提高代谢率对除吸烟外主要为代谢性的危险因素具有积极影响。因此,本文描述了运动时能量释放及其增加的生理方面。对预防而言,关键不在于运动的性质(例如耐力训练),而在于体力活动的总体程度以及由此产生的能量消耗。体力活动的血流动力学效应,尤其是心血管功能的优化,与其说是出于一级预防的原因,不如说是为了降低心肌的氧需求——这是一种二级预防措施。为产生心血管训练效果,接近有氧 - 无氧阈值(AAT)的运动形式最为理想。一个常见的错误是认为在生理条件下获得的训练效果可以简单地外推到病理生理情况。低于有氧 - 无氧阈值的运动负荷无法产生训练效果。在此,主要目标必须是实现代谢、协调和激励效果。如果运动的生理反应,特别是心率,因病理生理或药理机制而改变,则应使用其他参数,特别是呼吸和代谢参数作为训练的调节指标。本文将详细讨论这些参数。

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