Seki Masaaki, Togashi Hajime, Ando Noburo
Department of Ophthalmology, Saiseikai Niigata Daini Hospital, Niigata 950-1104, Japan.
Nippon Ganka Gakkai Zasshi. 2006 Jun;110(6):462-7.
To evaluate the incidence and risk factors of optic nerve atrophy after vitrectomy for diabetic retinopathy.
Clinical charts of 48 eyes of 40 patients who underwent vitrectomy for diabetic retinopathy were retrospectively reviewed. The relationship between postoperative optic nerve atrophy and patients' physical condition was statistically analyzed.
Postoperative optic nerve atrophy, distinct from glaucomatous optic nerve atrophy, occurred in 5 eyes (10.4%). Its incidence was correlated with higher plasma creatinine concentration (p=0.001), proliferative diabetic retinopathy (p= 0.046), and retinal white vessel formation (p= 0.007). Maintenance of the best postoperative visual acuity was difficult in the patients with optic nerve atrophy.
Patients with proliferative diabetic retinopathy accompanied by renal dysfunction were at high risk of optic nerve atrophy after vitrectomy.
评估糖尿病视网膜病变玻璃体切除术后视神经萎缩的发生率及危险因素。
回顾性分析40例接受糖尿病视网膜病变玻璃体切除术患者的48只眼的临床资料。对术后视神经萎缩与患者身体状况之间的关系进行统计学分析。
术后5只眼（10.4%）发生了与青光眼性视神经萎缩不同的视神经萎缩。其发生率与较高的血肌酐浓度（p = 0.001）、增殖性糖尿病视网膜病变（p = 0.046）和视网膜白色血管形成（p = 0.007）相关。视神经萎缩患者术后很难维持最佳视力。
增殖性糖尿病视网膜病变合并肾功能不全的患者玻璃体切除术后发生视神经萎缩的风险较高。
