Maeda Kimihito, Ishikawa Futoshi, Kobayashi Kazuo, Ohguro Hiroshi
Department of Ophthalmology, Sapporo Medical University School of Medicine, Sapporo-shi, Japan.
Nippon Ganka Gakkai Zasshi. 2009 Dec;113(12):1132-8.
To evaluate the optic nerve head blood flow level of a patient with proliferative diabetic retinopathy before and after vitrectomy, using laser speckle flow graphy (LSGF) for noninvasively ocular blood flow analysis.
Twenty three eyes of 23 patients were recruited in the present study who underwent vitrectomy at Sapporo Medical University hospital. We measured optic nerve head blood flow before and 2 weeks after operation. The average blood pressure and ocular perfusion pressure were measured before and after surgery.
Blood flow in the central retinal artery and on both the nasal and temporal sides of the optic nerve head significantly increased after surgery in all cases. In cases where the post-operative blood flow in the optic disk temporal side increased by more than 59%, visual acuity was also ameliorated.
LSFG is an effective method for evaluating the optic nerve head blood flow noninvasively, and may be useful for prediction of postoperative visual acuity prognosis.
