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青春期:冠心病风险长期追踪的关键时期?

Adolescence: a critical period for long-term tracking of risk for coronary heart disease?

作者信息

Ovesen Lars

机构信息

National Heart Foundation, Copenhagen, Denmark.

出版信息

Ann Nutr Metab. 2006;50(4):317-24. doi: 10.1159/000094294. Epub 2006 Jun 28.

Abstract

Tracking of dietary and physical activity patterns throughout adolescence into adulthood is low, which indicates that risk patterns for coronary heart disease are not maintained. Biological risk factors for heart disease, particularly obesity and clusters of nutritionally modifiable risk factors (e.g. the metabolic syndrome), display somewhat higher tracking correlations. Tracking gives little guidance as to how to use this information for screening purposes. For behavioral and biological risk factors predictive values and sensitivities and specificities are generally low, suggesting that population-based approaches are likely to be more effective than targeting only the high-risk subset for reducing the risk of coronary heart disease.

摘要

从青春期到成年期,饮食和身体活动模式的追踪情况较差,这表明冠心病的风险模式未能持续。心脏病的生物学风险因素,尤其是肥胖以及一系列可通过营养调节的风险因素(如代谢综合征),显示出略高的追踪相关性。追踪对于如何将这些信息用于筛查目的几乎没有指导作用。对于行为和生物学风险因素,预测值、敏感性和特异性通常较低,这表明基于人群的方法可能比仅针对高危亚组更有效地降低冠心病风险。

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