Morson B C, Volkstädt H
Research Department, St. Mark's Hospital, London.
J Clin Pathol. 1963 May;16(3):200-5. doi: 10.1136/jcp.16.3.200.
The pathology of 21 cases of muco-epidermoid carcinoma of the anal canal is described. These tumours are defined as squamous or transitional cell carcinomas containing areas which secrete mucin of undoubted epithelial origin within the clumps of tumour cells. They are found in that part of the anal canal just above the dentate line where the epithelium is variable in type and represents an embryological transition between rectal and squamous mucous membrane. The histogenesis of these tumours is discussed and the opinion given that they arise from the surface epithelium of the upper anal canal rather than from the anal glands.
本文描述了21例肛管黏液表皮样癌的病理情况。这些肿瘤被定义为鳞状或移行细胞癌,在肿瘤细胞团块内含有分泌无疑来源于上皮的黏液的区域。它们见于齿状线稍上方的肛管部位,此处上皮类型多变,代表直肠黏膜与鳞状黏膜之间的胚胎学过渡区域。文中讨论了这些肿瘤的组织发生,并认为它们起源于肛管上段的表面上皮,而非肛门腺。